Diabetogenic viruses: linking viruses to diabetes mellitus
Diabetes Mellitus (DM) is a group of chronic metabolic diseases distinguished by elevated glycemia due to the alterations in insulin metabolism. DM is one of the most relevant diseases of the modern world, with high incidence and prevalence worldwide, associated with severe systemic complications an...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-04-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023022284 |
| _version_ | 1797837007706128384 |
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| author | Bia Francis Rajsfus Ronaldo Mohana-Borges Diego Allonso |
| author_facet | Bia Francis Rajsfus Ronaldo Mohana-Borges Diego Allonso |
| author_sort | Bia Francis Rajsfus |
| collection | DOAJ |
| description | Diabetes Mellitus (DM) is a group of chronic metabolic diseases distinguished by elevated glycemia due to the alterations in insulin metabolism. DM is one of the most relevant diseases of the modern world, with high incidence and prevalence worldwide, associated with severe systemic complications and increased morbidity and mortality rates. Although genetic factors and lifestyle habits are two of the main factors involved in DM onset, viral infections, such as enteroviruses, cytomegalovirus, hepatitis C virus, human immunodeficiency virus, severe acute respiratory syndrome coronavirus 2, among others, have been linked as triggers of type 1 (T1DM) and type 2 (T2DM) diabetes. Over the years, various groups identified different mechanisms as to how viruses can promote these metabolic syndromes. However, this field is still poorly explored and needs further research, as millions of people live with these pathologies. Thus, this review aims to ex-plore the different processes of how viruses can induce DM and their contribution to the prevalence and incidence of DM worldwide. |
| first_indexed | 2024-04-09T15:17:59Z |
| format | Article |
| id | doaj.art-2b869fc317aa412081883f1386c6e8db |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-09T15:17:59Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-2b869fc317aa412081883f1386c6e8db2023-04-29T14:54:00ZengElsevierHeliyon2405-84402023-04-0194e15021Diabetogenic viruses: linking viruses to diabetes mellitusBia Francis Rajsfus0Ronaldo Mohana-Borges1Diego Allonso2Instituto de Biofísica Carlos Chagas Filho, Laboratório de Biotecnologia e Bioengenharia Estrutural, Universidade Federal do Rio de Janeiro, RJ, 21941-902, BrazilInstituto de Biofísica Carlos Chagas Filho, Laboratório de Biotecnologia e Bioengenharia Estrutural, Universidade Federal do Rio de Janeiro, RJ, 21941-902, BrazilDepartamento de Biotecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, RJ, 21941-902, Brazil; Corresponding author. Departamento de Biotecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, RJ 21942-902, Brazil.Diabetes Mellitus (DM) is a group of chronic metabolic diseases distinguished by elevated glycemia due to the alterations in insulin metabolism. DM is one of the most relevant diseases of the modern world, with high incidence and prevalence worldwide, associated with severe systemic complications and increased morbidity and mortality rates. Although genetic factors and lifestyle habits are two of the main factors involved in DM onset, viral infections, such as enteroviruses, cytomegalovirus, hepatitis C virus, human immunodeficiency virus, severe acute respiratory syndrome coronavirus 2, among others, have been linked as triggers of type 1 (T1DM) and type 2 (T2DM) diabetes. Over the years, various groups identified different mechanisms as to how viruses can promote these metabolic syndromes. However, this field is still poorly explored and needs further research, as millions of people live with these pathologies. Thus, this review aims to ex-plore the different processes of how viruses can induce DM and their contribution to the prevalence and incidence of DM worldwide.http://www.sciencedirect.com/science/article/pii/S2405844023022284Diabetogenic virusesdiabetes mellitusmetabolic syndrome |
| spellingShingle | Bia Francis Rajsfus Ronaldo Mohana-Borges Diego Allonso Diabetogenic viruses: linking viruses to diabetes mellitus Heliyon Diabetogenic viruses diabetes mellitus metabolic syndrome |
| title | Diabetogenic viruses: linking viruses to diabetes mellitus |
| title_full | Diabetogenic viruses: linking viruses to diabetes mellitus |
| title_fullStr | Diabetogenic viruses: linking viruses to diabetes mellitus |
| title_full_unstemmed | Diabetogenic viruses: linking viruses to diabetes mellitus |
| title_short | Diabetogenic viruses: linking viruses to diabetes mellitus |
| title_sort | diabetogenic viruses linking viruses to diabetes mellitus |
| topic | Diabetogenic viruses diabetes mellitus metabolic syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023022284 |
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