Stimulation of Eryptosis by Afatinib

Stimulation of Eryptosis by Afatinib

Background/Aims: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor afatinib is primarily utilized for the treatment of non-small cell lung carcinoma. The drug is at least partially effective by triggering suicidal tumor cell death. Side effects of afatinib treatment include anemi...

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Bibliographic Details
Main Authors: Abdulla Al Mamun Bhuyan, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Afatinib
Eryptosis
Phosphatidylserine
Calcium
Oxidative stress
Ceramide
Online Access:https://www.karger.com/Article/FullText/490221

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