Psychiatric Diagnoses and Medications in Wolfram Syndrome
Wolfram Syndrome is a rare genetic disorder usually resulting from pathogenic variation in the WFS1 gene, which leads to an exaggerated endoplasmic reticulum (ER) stress response. The disorder is typically characterized by diabetes insipidus, diabetes mellitus, optic nerve atrophy, hearing loss, and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2022-12-01
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| Series: | Scandinavian Journal of Child and Adolescent Psychiatry and Psychology |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/sjcapp-2022-0017 |
| _version_ | 1797947733164687360 |
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| author | Reiersen Angela M. Noel Jacob S. Doty Tasha Sinkre Richa A. Narayanan Anagha Hershey Tamara |
| author_facet | Reiersen Angela M. Noel Jacob S. Doty Tasha Sinkre Richa A. Narayanan Anagha Hershey Tamara |
| author_sort | Reiersen Angela M. |
| collection | DOAJ |
| description | Wolfram Syndrome is a rare genetic disorder usually resulting from pathogenic variation in the WFS1 gene, which leads to an exaggerated endoplasmic reticulum (ER) stress response. The disorder is typically characterized by diabetes insipidus, diabetes mellitus, optic nerve atrophy, hearing loss, and neurodegenerative features. Existing literature suggests it may also have psychiatric manifestations. |
| first_indexed | 2024-04-10T21:31:25Z |
| format | Article |
| id | doaj.art-2b8e2c5842ad48059e963c09b6b1c266 |
| institution | Directory Open Access Journal |
| issn | 2245-8875 |
| language | English |
| last_indexed | 2024-04-10T21:31:25Z |
| publishDate | 2022-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Scandinavian Journal of Child and Adolescent Psychiatry and Psychology |
| spelling | doaj.art-2b8e2c5842ad48059e963c09b6b1c2662023-01-19T13:20:28ZengSciendoScandinavian Journal of Child and Adolescent Psychiatry and Psychology2245-88752022-12-0110116317410.2478/sjcapp-2022-0017Psychiatric Diagnoses and Medications in Wolfram SyndromeReiersen Angela M.0Noel Jacob S.1Doty Tasha2Sinkre Richa A.3Narayanan Anagha4Hershey Tamara5Department of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri, United StatesDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri, United StatesDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri, United StatesDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri, United StatesDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri, United StatesDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri, United StatesWolfram Syndrome is a rare genetic disorder usually resulting from pathogenic variation in the WFS1 gene, which leads to an exaggerated endoplasmic reticulum (ER) stress response. The disorder is typically characterized by diabetes insipidus, diabetes mellitus, optic nerve atrophy, hearing loss, and neurodegenerative features. Existing literature suggests it may also have psychiatric manifestations.https://doi.org/10.2478/sjcapp-2022-0017wolfram syndromepsychiatryanxietyobsessive compulsive disordermedicationer stress |
| spellingShingle | Reiersen Angela M. Noel Jacob S. Doty Tasha Sinkre Richa A. Narayanan Anagha Hershey Tamara Psychiatric Diagnoses and Medications in Wolfram Syndrome Scandinavian Journal of Child and Adolescent Psychiatry and Psychology wolfram syndrome psychiatry anxiety obsessive compulsive disorder medication er stress |
| title | Psychiatric Diagnoses and Medications in Wolfram Syndrome |
| title_full | Psychiatric Diagnoses and Medications in Wolfram Syndrome |
| title_fullStr | Psychiatric Diagnoses and Medications in Wolfram Syndrome |
| title_full_unstemmed | Psychiatric Diagnoses and Medications in Wolfram Syndrome |
| title_short | Psychiatric Diagnoses and Medications in Wolfram Syndrome |
| title_sort | psychiatric diagnoses and medications in wolfram syndrome |
| topic | wolfram syndrome psychiatry anxiety obsessive compulsive disorder medication er stress |
| url | https://doi.org/10.2478/sjcapp-2022-0017 |
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