Malignant Syndrome in a Patient with Parkinson's Disease

Malignant syndrome during the course of Parkinson’s disease usually occurs because of withdrawal or dose reduction of anti-Parkinsonian drugs, especially levodopa and may be fatal. Fever, rigidity, autonomic disfunction, elevated creatinin kinase level and confusion are the major clinical findings....

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Bibliographic Details
Main Authors: Nesrin Helvacı Yılmaz, Gökçen Duymaz, Mehmet Akif Yaşar
Format: Article
Language:English
Published: Galenos Yayinevi 2012-09-01
Series:Türk Nöroloji Dergisi
Subjects:
Online Access:http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-39358
Description
Summary:Malignant syndrome during the course of Parkinson’s disease usually occurs because of withdrawal or dose reduction of anti-Parkinsonian drugs, especially levodopa and may be fatal. Fever, rigidity, autonomic disfunction, elevated creatinin kinase level and confusion are the major clinical findings. We aimed to present a patient that was treated in our intensive care unit in order to emphasise the importance of correct diagnosis of this disease, to discuss the precipitating factors and to highlight the importance of early treatment
ISSN:1301-062X
1309-2545