Malignant Syndrome in a Patient with Parkinson's Disease

Malignant syndrome during the course of Parkinson’s disease usually occurs because of withdrawal or dose reduction of anti-Parkinsonian drugs, especially levodopa and may be fatal. Fever, rigidity, autonomic disfunction, elevated creatinin kinase level and confusion are the major clinical findings....

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Main Authors: Nesrin Helvacı Yılmaz, Gökçen Duymaz, Mehmet Akif Yaşar
Format: Article
Language:English
Published: Galenos Yayinevi 2012-09-01
Series:Türk Nöroloji Dergisi
Subjects:
Online Access:http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-39358
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author Nesrin Helvacı Yılmaz
Gökçen Duymaz
Mehmet Akif Yaşar
author_facet Nesrin Helvacı Yılmaz
Gökçen Duymaz
Mehmet Akif Yaşar
author_sort Nesrin Helvacı Yılmaz
collection DOAJ
description Malignant syndrome during the course of Parkinson’s disease usually occurs because of withdrawal or dose reduction of anti-Parkinsonian drugs, especially levodopa and may be fatal. Fever, rigidity, autonomic disfunction, elevated creatinin kinase level and confusion are the major clinical findings. We aimed to present a patient that was treated in our intensive care unit in order to emphasise the importance of correct diagnosis of this disease, to discuss the precipitating factors and to highlight the importance of early treatment
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institution Directory Open Access Journal
issn 1301-062X
1309-2545
language English
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publishDate 2012-09-01
publisher Galenos Yayinevi
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series Türk Nöroloji Dergisi
spelling doaj.art-2b9003d1dbc64b34bde757c2853f15612023-02-15T16:21:44ZengGalenos YayineviTürk Nöroloji Dergisi1301-062X1309-25452012-09-0118312312510.4274/Tnd.39358Malignant Syndrome in a Patient with Parkinson's DiseaseNesrin Helvacı Yılmaz0Gökçen Duymaz1Mehmet Akif Yaşar2Department Of Neurology, Universal Group Hospital Aksaray, İstanbul, TurkeyDepartment Of Anesthesiology And ReanimationDepartment Of Anesthesiology And ReanimationMalignant syndrome during the course of Parkinson’s disease usually occurs because of withdrawal or dose reduction of anti-Parkinsonian drugs, especially levodopa and may be fatal. Fever, rigidity, autonomic disfunction, elevated creatinin kinase level and confusion are the major clinical findings. We aimed to present a patient that was treated in our intensive care unit in order to emphasise the importance of correct diagnosis of this disease, to discuss the precipitating factors and to highlight the importance of early treatmenthttp://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-39358Parkinson’s diseasemalignant syndromelevodopainfection
spellingShingle Nesrin Helvacı Yılmaz
Gökçen Duymaz
Mehmet Akif Yaşar
Malignant Syndrome in a Patient with Parkinson's Disease
Türk Nöroloji Dergisi
Parkinson’s disease
malignant syndrome
levodopa
infection
title Malignant Syndrome in a Patient with Parkinson's Disease
title_full Malignant Syndrome in a Patient with Parkinson's Disease
title_fullStr Malignant Syndrome in a Patient with Parkinson's Disease
title_full_unstemmed Malignant Syndrome in a Patient with Parkinson's Disease
title_short Malignant Syndrome in a Patient with Parkinson's Disease
title_sort malignant syndrome in a patient with parkinson s disease
topic Parkinson’s disease
malignant syndrome
levodopa
infection
url http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-39358
work_keys_str_mv AT nesrinhelvacıyılmaz malignantsyndromeinapatientwithparkinsonsdisease
AT gokcenduymaz malignantsyndromeinapatientwithparkinsonsdisease
AT mehmetakifyasar malignantsyndromeinapatientwithparkinsonsdisease