Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals
Our aim was to measure the concentrations of derived reactive oxygen metabolite (d-ROMs) and biological antioxidant potential (BAP) of donkey mares and foals at delivery and to verify the protective role of the placenta against fetal oxidative stress. A total of 15 Amiata jennies with a physiologica...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-10-01
|
Series: | Animals |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-2615/11/10/2885 |
_version_ | 1811153748239581184 |
---|---|
author | Micaela Sgorbini Francesca Bonelli Giulia Percacini Anna Pasquini Alessandra Rota |
author_facet | Micaela Sgorbini Francesca Bonelli Giulia Percacini Anna Pasquini Alessandra Rota |
author_sort | Micaela Sgorbini |
collection | DOAJ |
description | Our aim was to measure the concentrations of derived reactive oxygen metabolite (d-ROMs) and biological antioxidant potential (BAP) of donkey mares and foals at delivery and to verify the protective role of the placenta against fetal oxidative stress. A total of 15 Amiata jennies with a physiological gestation length and delivery were included together with 17 foals (two twin foalings). After delivery, maternal and foal venous blood samples were collected along with blood from the artery. Circulating lactate and plasma d-ROMs and BAP were evaluated. The Wilcoxon test for paired data was applied to verify differences in d-ROMs and BAP values, while the Spearman test was used to evaluate correlations. A significantly higher d-ROMs concentration was found in jennies compared to their foals, and to the umbilical artery blood. The BAP was higher in jennies than in their foals, but no differences were observed in the umbilical artery blood. No difference was found between foals and their umbilical cord. Blood lactate was higher in foals than in their dams. Positive correlations were found between mares and umbilical cord for BAP and d-ROMs, and between mares and foals and umbilical cord for BAP. In conclusion, the placenta may be a protective factor for the fetus. As with equine foals, the antioxidant system of donkey foals does not seems to be effective at birth. |
first_indexed | 2024-03-10T06:47:01Z |
format | Article |
id | doaj.art-2b914d3e0e1d46ebb31c3c7fbdedd8e3 |
institution | Directory Open Access Journal |
issn | 2076-2615 |
language | English |
last_indexed | 2024-03-10T06:47:01Z |
publishDate | 2021-10-01 |
publisher | MDPI AG |
record_format | Article |
series | Animals |
spelling | doaj.art-2b914d3e0e1d46ebb31c3c7fbdedd8e32023-11-22T17:10:42ZengMDPI AGAnimals2076-26152021-10-011110288510.3390/ani11102885Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and FoalsMicaela Sgorbini0Francesca Bonelli1Giulia Percacini2Anna Pasquini3Alessandra Rota4Department of Veterinary Sciences, Veterinary Teaching Hospital, Via Livornese, San Piero a Grado, 56122 Pisa, ItalyDepartment of Veterinary Sciences, Veterinary Teaching Hospital, Via Livornese, San Piero a Grado, 56122 Pisa, ItalyVeterinary Practitioner, 16121 Genova, ItalyDepartment of Veterinary Sciences, Veterinary Teaching Hospital, Via Livornese, San Piero a Grado, 56122 Pisa, ItalyDepartment of Veterinary Sciences, Veterinary Teaching Hospital, Via Livornese, San Piero a Grado, 56122 Pisa, ItalyOur aim was to measure the concentrations of derived reactive oxygen metabolite (d-ROMs) and biological antioxidant potential (BAP) of donkey mares and foals at delivery and to verify the protective role of the placenta against fetal oxidative stress. A total of 15 Amiata jennies with a physiological gestation length and delivery were included together with 17 foals (two twin foalings). After delivery, maternal and foal venous blood samples were collected along with blood from the artery. Circulating lactate and plasma d-ROMs and BAP were evaluated. The Wilcoxon test for paired data was applied to verify differences in d-ROMs and BAP values, while the Spearman test was used to evaluate correlations. A significantly higher d-ROMs concentration was found in jennies compared to their foals, and to the umbilical artery blood. The BAP was higher in jennies than in their foals, but no differences were observed in the umbilical artery blood. No difference was found between foals and their umbilical cord. Blood lactate was higher in foals than in their dams. Positive correlations were found between mares and umbilical cord for BAP and d-ROMs, and between mares and foals and umbilical cord for BAP. In conclusion, the placenta may be a protective factor for the fetus. As with equine foals, the antioxidant system of donkey foals does not seems to be effective at birth.https://www.mdpi.com/2076-2615/11/10/2885oxidative statusBAPd-ROMsdonkey foaldonkey mare |
spellingShingle | Micaela Sgorbini Francesca Bonelli Giulia Percacini Anna Pasquini Alessandra Rota Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals Animals oxidative status BAP d-ROMs donkey foal donkey mare |
title | Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals |
title_full | Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals |
title_fullStr | Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals |
title_full_unstemmed | Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals |
title_short | Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals |
title_sort | maternal and neonatal evaluation of derived reactive oxygen metabolites and biological antioxidant potential in donkey mares and foals |
topic | oxidative status BAP d-ROMs donkey foal donkey mare |
url | https://www.mdpi.com/2076-2615/11/10/2885 |
work_keys_str_mv | AT micaelasgorbini maternalandneonatalevaluationofderivedreactiveoxygenmetabolitesandbiologicalantioxidantpotentialindonkeymaresandfoals AT francescabonelli maternalandneonatalevaluationofderivedreactiveoxygenmetabolitesandbiologicalantioxidantpotentialindonkeymaresandfoals AT giuliapercacini maternalandneonatalevaluationofderivedreactiveoxygenmetabolitesandbiologicalantioxidantpotentialindonkeymaresandfoals AT annapasquini maternalandneonatalevaluationofderivedreactiveoxygenmetabolitesandbiologicalantioxidantpotentialindonkeymaresandfoals AT alessandrarota maternalandneonatalevaluationofderivedreactiveoxygenmetabolitesandbiologicalantioxidantpotentialindonkeymaresandfoals |