Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals

Our aim was to measure the concentrations of derived reactive oxygen metabolite (d-ROMs) and biological antioxidant potential (BAP) of donkey mares and foals at delivery and to verify the protective role of the placenta against fetal oxidative stress. A total of 15 Amiata jennies with a physiologica...

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Main Authors: Micaela Sgorbini, Francesca Bonelli, Giulia Percacini, Anna Pasquini, Alessandra Rota
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/11/10/2885
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author Micaela Sgorbini
Francesca Bonelli
Giulia Percacini
Anna Pasquini
Alessandra Rota
author_facet Micaela Sgorbini
Francesca Bonelli
Giulia Percacini
Anna Pasquini
Alessandra Rota
author_sort Micaela Sgorbini
collection DOAJ
description Our aim was to measure the concentrations of derived reactive oxygen metabolite (d-ROMs) and biological antioxidant potential (BAP) of donkey mares and foals at delivery and to verify the protective role of the placenta against fetal oxidative stress. A total of 15 Amiata jennies with a physiological gestation length and delivery were included together with 17 foals (two twin foalings). After delivery, maternal and foal venous blood samples were collected along with blood from the artery. Circulating lactate and plasma d-ROMs and BAP were evaluated. The Wilcoxon test for paired data was applied to verify differences in d-ROMs and BAP values, while the Spearman test was used to evaluate correlations. A significantly higher d-ROMs concentration was found in jennies compared to their foals, and to the umbilical artery blood. The BAP was higher in jennies than in their foals, but no differences were observed in the umbilical artery blood. No difference was found between foals and their umbilical cord. Blood lactate was higher in foals than in their dams. Positive correlations were found between mares and umbilical cord for BAP and d-ROMs, and between mares and foals and umbilical cord for BAP. In conclusion, the placenta may be a protective factor for the fetus. As with equine foals, the antioxidant system of donkey foals does not seems to be effective at birth.
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spelling doaj.art-2b914d3e0e1d46ebb31c3c7fbdedd8e32023-11-22T17:10:42ZengMDPI AGAnimals2076-26152021-10-011110288510.3390/ani11102885Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and FoalsMicaela Sgorbini0Francesca Bonelli1Giulia Percacini2Anna Pasquini3Alessandra Rota4Department of Veterinary Sciences, Veterinary Teaching Hospital, Via Livornese, San Piero a Grado, 56122 Pisa, ItalyDepartment of Veterinary Sciences, Veterinary Teaching Hospital, Via Livornese, San Piero a Grado, 56122 Pisa, ItalyVeterinary Practitioner, 16121 Genova, ItalyDepartment of Veterinary Sciences, Veterinary Teaching Hospital, Via Livornese, San Piero a Grado, 56122 Pisa, ItalyDepartment of Veterinary Sciences, Veterinary Teaching Hospital, Via Livornese, San Piero a Grado, 56122 Pisa, ItalyOur aim was to measure the concentrations of derived reactive oxygen metabolite (d-ROMs) and biological antioxidant potential (BAP) of donkey mares and foals at delivery and to verify the protective role of the placenta against fetal oxidative stress. A total of 15 Amiata jennies with a physiological gestation length and delivery were included together with 17 foals (two twin foalings). After delivery, maternal and foal venous blood samples were collected along with blood from the artery. Circulating lactate and plasma d-ROMs and BAP were evaluated. The Wilcoxon test for paired data was applied to verify differences in d-ROMs and BAP values, while the Spearman test was used to evaluate correlations. A significantly higher d-ROMs concentration was found in jennies compared to their foals, and to the umbilical artery blood. The BAP was higher in jennies than in their foals, but no differences were observed in the umbilical artery blood. No difference was found between foals and their umbilical cord. Blood lactate was higher in foals than in their dams. Positive correlations were found between mares and umbilical cord for BAP and d-ROMs, and between mares and foals and umbilical cord for BAP. In conclusion, the placenta may be a protective factor for the fetus. As with equine foals, the antioxidant system of donkey foals does not seems to be effective at birth.https://www.mdpi.com/2076-2615/11/10/2885oxidative statusBAPd-ROMsdonkey foaldonkey mare
spellingShingle Micaela Sgorbini
Francesca Bonelli
Giulia Percacini
Anna Pasquini
Alessandra Rota
Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals
Animals
oxidative status
BAP
d-ROMs
donkey foal
donkey mare
title Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals
title_full Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals
title_fullStr Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals
title_full_unstemmed Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals
title_short Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals
title_sort maternal and neonatal evaluation of derived reactive oxygen metabolites and biological antioxidant potential in donkey mares and foals
topic oxidative status
BAP
d-ROMs
donkey foal
donkey mare
url https://www.mdpi.com/2076-2615/11/10/2885
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AT francescabonelli maternalandneonatalevaluationofderivedreactiveoxygenmetabolitesandbiologicalantioxidantpotentialindonkeymaresandfoals
AT giuliapercacini maternalandneonatalevaluationofderivedreactiveoxygenmetabolitesandbiologicalantioxidantpotentialindonkeymaresandfoals
AT annapasquini maternalandneonatalevaluationofderivedreactiveoxygenmetabolitesandbiologicalantioxidantpotentialindonkeymaresandfoals
AT alessandrarota maternalandneonatalevaluationofderivedreactiveoxygenmetabolitesandbiologicalantioxidantpotentialindonkeymaresandfoals