New hybrid radio-fluorescent probes [131I]-BPF-01 and [131I]-BPF-02 for visualisation of cancer cells: Synthesis and preliminary in vitro and ex vivo evaluations

New hybrid radio-fluorescent probes [131I]-BPF-01 and [131I]-BPF-02 for visualisation of cancer cells: Synthesis and preliminary in vitro and ex vivo evaluations

We synthesised and biologically evaluated two new hybrid probes [131I]BPF-01 and [131I]BPF-02 which were built from three structural entities: benzothiazole-phenyl, fluorescein isothiocyanate (FITC), and iodine-131. These probes were designed for potential applications in assisting surgical procedur...

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Bibliographic Details
Main Authors: Hendris Wongso, Ahmad Kurniawan, Alfian M. Forentin, Veronika Y. Susilo, Yanuar Setiadi, Isa Mahendra, Muhamad B. Febrian, Aziiz M. Rosdianto, Iwan Setiawan, Hanna Goenawan, Susianti Susianti, Unang Supratman, Eva M. Widyasari, Teguh H.A. Wibawa, Maula E. Sriyani, Iim Halimah, Ronny Lesmana
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Heliyon
Subjects:
Fluorescent
Hybrid radio-fluorescent
Solid cancers
Imaging
Image-guided surgery
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023079185

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