Engraftment of Allotransplanted Tumor Cells in Adult <i>rag2</i> Mutant <i>Xenopus tropicalis</i>

Engraftment of Allotransplanted Tumor Cells in Adult <i>rag2</i> Mutant <i>Xenopus tropicalis</i>

Modeling human genetic diseases and cancer in lab animals has been greatly aided by the emergence of genetic engineering tools such as TALENs and CRISPR/Cas9. We have previously demonstrated the ease with which genetically engineered <i>Xenopus</i> models (GEXM) can be generated via inje...

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Bibliographic Details
Main Authors: Dieter Tulkens, Dionysia Dimitrakopoulou, Marthe Boelens, Tom Van Nieuwenhuysen, Suzan Demuynck, Wendy Toussaint, David Creytens, Pieter Van Vlierberghe, Kris Vleminckx
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
<i>Xenopus</i>
tumor transplantations
genetic cancer model
<i>rag2</i> knockout
immunocompromised
Online Access:https://www.mdpi.com/2072-6694/14/19/4560

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