A Comprehensive Computational Investigation into the Conserved Virulent Proteins of <i>Shigella</i> species Unveils Potential Small-Interfering RNA Candidates as a New Therapeutic Strategy against Shigellosis

A Comprehensive Computational Investigation into the Conserved Virulent Proteins of <i>Shigella</i> species Unveils Potential Small-Interfering RNA Candidates as a New Therapeutic Strategy against Shigellosis

<i>Shigella</i> species account for the second-leading cause of deaths due to diarrheal diseases among children of less than 5 years of age. The emergence of multi-drug-resistant <i>Shigella</i> isolates and the lack of availability of <i>Shigella</i> vaccines hav...

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Bibliographic Details
Main Authors: Parag Palit, Farhana Tasnim Chowdhury, Namrata Baruah, Bonoshree Sarkar, Sadia Noor Mou, Mehnaz Kamal, Towfida Jahan Siddiqua, Zannatun Noor, Tahmeed Ahmed
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
<i>Shigella</i>
small-interfering RNA
computational algorithms
RNAi pathway
shigellosis
Online Access:https://www.mdpi.com/1420-3049/27/6/1936

Internet

https://www.mdpi.com/1420-3049/27/6/1936

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