Design of new reversible and selective inhibitors of monoamine oxidase A and a comparison with drugs already approved
Abstract Background Monoamine oxidase (MAO) is an enzyme that has been targeted pharmacologically for the treatment of depression and neurodegenerative diseases such as Parkinson's disease. To avoid side effects, drugs currently in use must selectively target either of the enzyme's two iso...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2023-03-01
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Series: | Bulletin of the National Research Centre |
Subjects: | |
Online Access: | https://doi.org/10.1186/s42269-023-01018-9 |