Design of new reversible and selective inhibitors of monoamine oxidase A and a comparison with drugs already approved

Abstract Background Monoamine oxidase (MAO) is an enzyme that has been targeted pharmacologically for the treatment of depression and neurodegenerative diseases such as Parkinson's disease. To avoid side effects, drugs currently in use must selectively target either of the enzyme's two iso...

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Bibliographic Details
Main Authors: A. Reyes-Chaparro, N. S. Flores-Lopez, F. Quintanilla-Guerrero, Dulce Estefanía Nicolás-Álvarez, A. R. Hernandez-Martinez
Format: Article
Language:English
Published: SpringerOpen 2023-03-01
Series:Bulletin of the National Research Centre
Subjects:
Online Access:https://doi.org/10.1186/s42269-023-01018-9