Antifouling Metabolites from the Mangrove Plant Ceriops tagal

The new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three knownmetabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and β-sitosterol (4), wereisolated from the roots of the mangrove plant Ceriops tagal. Their structures and relativestereochemistry were elucidated by means o...

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Main Authors: Yi Ming Lin, Yan Qiu, Zhan Chang Wang, Zhi Wei Yang, Dan Qin Feng, Jun De Chen
Format: Article
Language:English
Published: MDPI AG 2008-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/13/2/212/
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author Yi Ming Lin
Yan Qiu
Zhan Chang Wang
Zhi Wei Yang
Dan Qin Feng
Jun De Chen
author_facet Yi Ming Lin
Yan Qiu
Zhan Chang Wang
Zhi Wei Yang
Dan Qin Feng
Jun De Chen
author_sort Yi Ming Lin
collection DOAJ
description The new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three knownmetabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and β-sitosterol (4), wereisolated from the roots of the mangrove plant Ceriops tagal. Their structures and relativestereochemistry were elucidated by means of extensive NMR, IR and MS analysis.Compounds 1, 2, 3 and 4 exhibited significant antifouling activities against cyprid larvaeof the barnacle Balanus albicostatus Pilsbry, with EC50 values of 0.32 ± 0.01, 0.04 ± 0.00,4.05 ± 0.15 and 18.47 ± 0.40 μg/cm2, respectively, whereas their toxicities towards cypridswere very low, with LC50 values all above 10 μg/cm2.
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spelling doaj.art-2b9b712e7f784912b3afe07cd96924972022-12-21T18:30:46ZengMDPI AGMolecules1420-30492008-01-0113221221910.3390/molecules13020212Antifouling Metabolites from the Mangrove Plant Ceriops tagalYi Ming LinYan QiuZhan Chang WangZhi Wei YangDan Qin FengJun De ChenThe new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three knownmetabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and β-sitosterol (4), wereisolated from the roots of the mangrove plant Ceriops tagal. Their structures and relativestereochemistry were elucidated by means of extensive NMR, IR and MS analysis.Compounds 1, 2, 3 and 4 exhibited significant antifouling activities against cyprid larvaeof the barnacle Balanus albicostatus Pilsbry, with EC50 values of 0.32 ± 0.01, 0.04 ± 0.00,4.05 ± 0.15 and 18.47 ± 0.40 μg/cm2, respectively, whereas their toxicities towards cypridswere very low, with LC50 values all above 10 μg/cm2.http://www.mdpi.com/1420-3049/13/2/212/Diterpenesantifouling activitybarnacleCeriops tagal
spellingShingle Yi Ming Lin
Yan Qiu
Zhan Chang Wang
Zhi Wei Yang
Dan Qin Feng
Jun De Chen
Antifouling Metabolites from the Mangrove Plant Ceriops tagal
Molecules
Diterpenes
antifouling activity
barnacle
Ceriops tagal
title Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_full Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_fullStr Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_full_unstemmed Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_short Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_sort antifouling metabolites from the mangrove plant ceriops tagal
topic Diterpenes
antifouling activity
barnacle
Ceriops tagal
url http://www.mdpi.com/1420-3049/13/2/212/
work_keys_str_mv AT yiminglin antifoulingmetabolitesfromthemangroveplantceriopstagal
AT yanqiu antifoulingmetabolitesfromthemangroveplantceriopstagal
AT zhanchangwang antifoulingmetabolitesfromthemangroveplantceriopstagal
AT zhiweiyang antifoulingmetabolitesfromthemangroveplantceriopstagal
AT danqinfeng antifoulingmetabolitesfromthemangroveplantceriopstagal
AT jundechen antifoulingmetabolitesfromthemangroveplantceriopstagal