Bolus streptokinase administration in acute myocardial infarction: features of hypotensive reaction
Hypotension prevalence and severity was investigated in two regimens of streptokinase (SK) administration in acute myocardial infarction (AMI). Group I (n = 17) received intravenous SK, 0.75 mln IE, in 10 minutes; Group II (n = 9) - 1.5 mln IE, in 45 minutes. In bolus SK administration, maximal bloo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2005-04-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2464 |
| _version_ | 1797857274497073152 |
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| author | V. A. Stolyarov I. V. Maksimov V. A. Markov |
| author_facet | V. A. Stolyarov I. V. Maksimov V. A. Markov |
| author_sort | V. A. Stolyarov |
| collection | DOAJ |
| description | Hypotension prevalence and severity was investigated in two regimens of streptokinase (SK) administration in acute myocardial infarction (AMI). Group I (n = 17) received intravenous SK, 0.75 mln IE, in 10 minutes; Group II (n = 9) - 1.5 mln IE, in 45 minutes. In bolus SK administration, maximal blood pressure (BP) decrease was comparable to that in slow infusion group, but observed earlier - at minute 7.5 ± 0,4, vs minute 12.5 ± 6.8 (p = 0.003). In Group I, 3 cases of collapse were registered, with little effect from mezaton administration. Significant BPfall could be expected in patients with posterior MI, right wall damage and bradycardia. To prevent severe hypotensive reaction, bolus SK administration should be optimized. |
| first_indexed | 2024-04-09T20:54:01Z |
| format | Article |
| id | doaj.art-2b9dabfc8e6841f08f245025986a390e |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:54:01Z |
| publishDate | 2005-04-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-2b9dabfc8e6841f08f245025986a390e2023-03-29T21:23:11Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202005-04-010238422192Bolus streptokinase administration in acute myocardial infarction: features of hypotensive reactionV. A. Stolyarov0I. V. Maksimov1V. A. Markov2НИИ кардиологии Томского научного центра СО РАМННИИ кардиологии Томского научного центра СО РАМННИИ кардиологии Томского научного центра СО РАМНHypotension prevalence and severity was investigated in two regimens of streptokinase (SK) administration in acute myocardial infarction (AMI). Group I (n = 17) received intravenous SK, 0.75 mln IE, in 10 minutes; Group II (n = 9) - 1.5 mln IE, in 45 minutes. In bolus SK administration, maximal blood pressure (BP) decrease was comparable to that in slow infusion group, but observed earlier - at minute 7.5 ± 0,4, vs minute 12.5 ± 6.8 (p = 0.003). In Group I, 3 cases of collapse were registered, with little effect from mezaton administration. Significant BPfall could be expected in patients with posterior MI, right wall damage and bradycardia. To prevent severe hypotensive reaction, bolus SK administration should be optimized.https://russjcardiol.elpub.ru/jour/article/view/2464myocardial infarctionstreptokinasehypotensionno |
| spellingShingle | V. A. Stolyarov I. V. Maksimov V. A. Markov Bolus streptokinase administration in acute myocardial infarction: features of hypotensive reaction Российский кардиологический журнал myocardial infarction streptokinase hypotension no |
| title | Bolus streptokinase administration in acute myocardial infarction: features of hypotensive reaction |
| title_full | Bolus streptokinase administration in acute myocardial infarction: features of hypotensive reaction |
| title_fullStr | Bolus streptokinase administration in acute myocardial infarction: features of hypotensive reaction |
| title_full_unstemmed | Bolus streptokinase administration in acute myocardial infarction: features of hypotensive reaction |
| title_short | Bolus streptokinase administration in acute myocardial infarction: features of hypotensive reaction |
| title_sort | bolus streptokinase administration in acute myocardial infarction features of hypotensive reaction |
| topic | myocardial infarction streptokinase hypotension no |
| url | https://russjcardiol.elpub.ru/jour/article/view/2464 |
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