GSK-3β and Memory Formation

GSK-3β and Memory Formation

In Alzheimer’s disease (AD), tau hyperphosphorylation and neurofibrillary tangle (NFT) formation are strongly associated with dementia. Memory impairment is a characteristic, early symptom of AD. Glycogen synthase kinase 3 β (GSK-3β), which is activated in response to amyloid β (Aβ) formation,...

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Bibliographic Details
Main Author:	Akihiko eTakashima
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2012-04-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	Aging Alzheimer's disease tau memory formation memory impairment
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00047/full

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