Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT)
ABSTRACTExercise is a universally acknowledged and healthy way to reducing body weight. However, the roles and mechanisms of exercise on metabolism of adipose tissue remain largely unclear. Adipose tissues include white adipose tissue (WAT), brown adipose tissue (BAT) and beige adipose tissue (BeAT)...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2023-12-01
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| Series: | Adipocyte |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21623945.2023.2266147 |
| _version_ | 1827380589836107776 |
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| author | Haijun Dong Man Qin Peng Wang Shufan Li Xing Wang |
| author_facet | Haijun Dong Man Qin Peng Wang Shufan Li Xing Wang |
| author_sort | Haijun Dong |
| collection | DOAJ |
| description | ABSTRACTExercise is a universally acknowledged and healthy way to reducing body weight. However, the roles and mechanisms of exercise on metabolism of adipose tissue remain largely unclear. Adipose tissues include white adipose tissue (WAT), brown adipose tissue (BAT) and beige adipose tissue (BeAT). The main function of WAT is to store energy, while the BAT and BeAT can generate heat and consume energy. Therefore, promotion of BAT activation and WAT browning contributes to body weight loss. To date, many studies have suggested that exercise exerts the potential regulatory effects on BAT activation and WAT browning. In the present review, we compile the evidence for the regulatory effects of exercise on BAT activation and WAT browning and summarize the possible mechanisms whereby exercise modulates BAT activation and WAT browning, including activating sympathetic nervous system (SNS) and promoting the secretion of exerkines, with special focus on exerkines. These data might provide reference for prevention or treatment of obesity and the related metabolic disease through exercise. |
| first_indexed | 2024-03-08T13:37:06Z |
| format | Article |
| id | doaj.art-2ba555d6e10b4f8593e2b96ca03b0bb4 |
| institution | Directory Open Access Journal |
| issn | 2162-3945 2162-397X |
| language | English |
| last_indexed | 2024-03-08T13:37:06Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Adipocyte |
| spelling | doaj.art-2ba555d6e10b4f8593e2b96ca03b0bb42024-01-16T15:50:36ZengTaylor & Francis GroupAdipocyte2162-39452162-397X2023-12-0112110.1080/21623945.2023.2266147Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT)Haijun Dong0Man Qin1Peng Wang2Shufan Li3Xing Wang4Department of Physical Education, University of Shanghai for Science and Technology, Shanghai, ChinaSchool of Sports and Health, Shanghai Lixin Accounting and Finance University, Shanghai, ChinaSchool of Physical Education, Shanghai University of Sport, Shanghai, ChinaSchool of Physical Education, Shanghai University of Sport, Shanghai, ChinaSchool of Physical Education, Shanghai University of Sport, Shanghai, ChinaABSTRACTExercise is a universally acknowledged and healthy way to reducing body weight. However, the roles and mechanisms of exercise on metabolism of adipose tissue remain largely unclear. Adipose tissues include white adipose tissue (WAT), brown adipose tissue (BAT) and beige adipose tissue (BeAT). The main function of WAT is to store energy, while the BAT and BeAT can generate heat and consume energy. Therefore, promotion of BAT activation and WAT browning contributes to body weight loss. To date, many studies have suggested that exercise exerts the potential regulatory effects on BAT activation and WAT browning. In the present review, we compile the evidence for the regulatory effects of exercise on BAT activation and WAT browning and summarize the possible mechanisms whereby exercise modulates BAT activation and WAT browning, including activating sympathetic nervous system (SNS) and promoting the secretion of exerkines, with special focus on exerkines. These data might provide reference for prevention or treatment of obesity and the related metabolic disease through exercise.https://www.tandfonline.com/doi/10.1080/21623945.2023.2266147ObesityBAT activationWAT browningexerciseexerkines |
| spellingShingle | Haijun Dong Man Qin Peng Wang Shufan Li Xing Wang Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT) Adipocyte Obesity BAT activation WAT browning exercise exerkines |
| title | Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT) |
| title_full | Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT) |
| title_fullStr | Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT) |
| title_full_unstemmed | Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT) |
| title_short | Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT) |
| title_sort | regulatory effects and mechanisms of exercise on activation of brown adipose tissue bat and browning of white adipose tissue wat |
| topic | Obesity BAT activation WAT browning exercise exerkines |
| url | https://www.tandfonline.com/doi/10.1080/21623945.2023.2266147 |
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