An Update on Applications of Cattle Mesenchymal Stromal Cells
Attention on mesenchymal stromal cells (MSCs) research has increased in the last decade mainly due to the promising results about their plasticity, self-renewal, differentiation potential, immune modulatory and anti-inflammatory properties that have made stem cell therapy more clinically attractive....
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/15/1956 |
| _version_ | 1797442999114792960 |
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| author | Barbara Merlo Penelope Maria Gugole Eleonora Iacono |
| author_facet | Barbara Merlo Penelope Maria Gugole Eleonora Iacono |
| author_sort | Barbara Merlo |
| collection | DOAJ |
| description | Attention on mesenchymal stromal cells (MSCs) research has increased in the last decade mainly due to the promising results about their plasticity, self-renewal, differentiation potential, immune modulatory and anti-inflammatory properties that have made stem cell therapy more clinically attractive. Furthermore, MSCs can be easily isolated and expanded to be used for autologous or allogenic therapy following the administration of either freshly isolated or previously cryopreserved cells. The scientific literature on the use of stromal cells in the treatment of several animal health conditions is currently available. Although MSCs are not as widely used for clinical treatments in cows as for companion and sport animals, they have the potential to be employed to improve productivity in the cattle industry. This review provides an update on state-of-the-art applications of bovine MSCs to clinical treatments and reproductive biotechnologies. |
| first_indexed | 2024-03-09T12:49:45Z |
| format | Article |
| id | doaj.art-2bac5e20852e48af9baab82f0b30ab71 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T12:49:45Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-2bac5e20852e48af9baab82f0b30ab712023-11-30T22:07:44ZengMDPI AGAnimals2076-26152022-08-011215195610.3390/ani12151956An Update on Applications of Cattle Mesenchymal Stromal CellsBarbara Merlo0Penelope Maria Gugole1Eleonora Iacono2Department of Veterinary Medical Sciences, University of Bologna, 40064 Ozzano Emilia, BO, ItalyDepartment of Veterinary Medical Sciences, University of Bologna, 40064 Ozzano Emilia, BO, ItalyDepartment of Veterinary Medical Sciences, University of Bologna, 40064 Ozzano Emilia, BO, ItalyAttention on mesenchymal stromal cells (MSCs) research has increased in the last decade mainly due to the promising results about their plasticity, self-renewal, differentiation potential, immune modulatory and anti-inflammatory properties that have made stem cell therapy more clinically attractive. Furthermore, MSCs can be easily isolated and expanded to be used for autologous or allogenic therapy following the administration of either freshly isolated or previously cryopreserved cells. The scientific literature on the use of stromal cells in the treatment of several animal health conditions is currently available. Although MSCs are not as widely used for clinical treatments in cows as for companion and sport animals, they have the potential to be employed to improve productivity in the cattle industry. This review provides an update on state-of-the-art applications of bovine MSCs to clinical treatments and reproductive biotechnologies.https://www.mdpi.com/2076-2615/12/15/1956bovinemesenchymal stromal cellsclinical applicationsreproductive biotechnologies |
| spellingShingle | Barbara Merlo Penelope Maria Gugole Eleonora Iacono An Update on Applications of Cattle Mesenchymal Stromal Cells Animals bovine mesenchymal stromal cells clinical applications reproductive biotechnologies |
| title | An Update on Applications of Cattle Mesenchymal Stromal Cells |
| title_full | An Update on Applications of Cattle Mesenchymal Stromal Cells |
| title_fullStr | An Update on Applications of Cattle Mesenchymal Stromal Cells |
| title_full_unstemmed | An Update on Applications of Cattle Mesenchymal Stromal Cells |
| title_short | An Update on Applications of Cattle Mesenchymal Stromal Cells |
| title_sort | update on applications of cattle mesenchymal stromal cells |
| topic | bovine mesenchymal stromal cells clinical applications reproductive biotechnologies |
| url | https://www.mdpi.com/2076-2615/12/15/1956 |
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