Musculoskeletal modelling of the lumbar spine to explore functional interactions between back muscle loads and intervertebral disc multiphysics
During daily activities, complex biomechanical interactions influence the biophysical regulation of intervertebral discs (IVDs), and transfers of mechanical loads are largely controlled by the stabilizing action of spine muscles. Muscle and other internal forces cannot be easily measured directly in...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-08-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00111/full |
| _version_ | 1818848962070708224 |
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| author | Themis eToumanidou Themis eToumanidou Jérôme eNoailly Jérôme eNoailly |
| author_facet | Themis eToumanidou Themis eToumanidou Jérôme eNoailly Jérôme eNoailly |
| author_sort | Themis eToumanidou |
| collection | DOAJ |
| description | During daily activities, complex biomechanical interactions influence the biophysical regulation of intervertebral discs (IVDs), and transfers of mechanical loads are largely controlled by the stabilizing action of spine muscles. Muscle and other internal forces cannot be easily measured directly in the lumbar spine. Hence, biomechanical models are important tools for the evaluation of the loads in those tissues involved in low back disorders. Muscle force estimations in most musculoskeletal models mainly rely, however, on inverse calculations and static optimizations that limit the predictive power of the numerical calculations. In order to contribute to the development of predictive systems, we coupled a predictive muscle model with the passive resistance of the spine tissues, in a L3-S1 musculoskeletal finite element model with osmo-poromechanical IVD descriptions. The model included 46 fascicles of the major back muscles that act on the lower spine. The muscle model interacted with activity-related loads imposed to the osteoligamentous structure, as standing position and night rest were simulated through distributed upper body mass and free IVD swelling, respectively. Calculations led to intradiscal pressure values within ranges of values measured in vivo. Disc swelling led to muscle activation and muscle force distributions that seemed particularly appropriate to counterbalance the anterior body mass effect in standing. Our simulations pointed out a likely existence of a functional balance between stretch-induced muscle activation and IVD multiphysics towards improved mechanical stability of the lumbar spine under standing. This balance suggests that proper night rest contributes to mechanically strengthen the spine during day activity. |
| first_indexed | 2024-12-19T06:25:40Z |
| format | Article |
| id | doaj.art-2bacc15a4e3c40c88277826d357b8388 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-12-19T06:25:40Z |
| publishDate | 2015-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-2bacc15a4e3c40c88277826d357b83882022-12-21T20:32:34ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852015-08-01310.3389/fbioe.2015.00111147606Musculoskeletal modelling of the lumbar spine to explore functional interactions between back muscle loads and intervertebral disc multiphysicsThemis eToumanidou0Themis eToumanidou1Jérôme eNoailly2Jérôme eNoailly3Institute for Bioengineering of Catalonia (IBEC)Universitat Pompeu FabraUniversitat Pompeu FabraInstitute for Bioengineering of Catalonia (IBEC)During daily activities, complex biomechanical interactions influence the biophysical regulation of intervertebral discs (IVDs), and transfers of mechanical loads are largely controlled by the stabilizing action of spine muscles. Muscle and other internal forces cannot be easily measured directly in the lumbar spine. Hence, biomechanical models are important tools for the evaluation of the loads in those tissues involved in low back disorders. Muscle force estimations in most musculoskeletal models mainly rely, however, on inverse calculations and static optimizations that limit the predictive power of the numerical calculations. In order to contribute to the development of predictive systems, we coupled a predictive muscle model with the passive resistance of the spine tissues, in a L3-S1 musculoskeletal finite element model with osmo-poromechanical IVD descriptions. The model included 46 fascicles of the major back muscles that act on the lower spine. The muscle model interacted with activity-related loads imposed to the osteoligamentous structure, as standing position and night rest were simulated through distributed upper body mass and free IVD swelling, respectively. Calculations led to intradiscal pressure values within ranges of values measured in vivo. Disc swelling led to muscle activation and muscle force distributions that seemed particularly appropriate to counterbalance the anterior body mass effect in standing. Our simulations pointed out a likely existence of a functional balance between stretch-induced muscle activation and IVD multiphysics towards improved mechanical stability of the lumbar spine under standing. This balance suggests that proper night rest contributes to mechanically strengthen the spine during day activity.http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00111/fullstandingnight restConstitutive muscle modelLumbar spine finite element modelIntervertebral disc swellingIntervertebral disc-muscle interaction |
| spellingShingle | Themis eToumanidou Themis eToumanidou Jérôme eNoailly Jérôme eNoailly Musculoskeletal modelling of the lumbar spine to explore functional interactions between back muscle loads and intervertebral disc multiphysics Frontiers in Bioengineering and Biotechnology standing night rest Constitutive muscle model Lumbar spine finite element model Intervertebral disc swelling Intervertebral disc-muscle interaction |
| title | Musculoskeletal modelling of the lumbar spine to explore functional interactions between back muscle loads and intervertebral disc multiphysics |
| title_full | Musculoskeletal modelling of the lumbar spine to explore functional interactions between back muscle loads and intervertebral disc multiphysics |
| title_fullStr | Musculoskeletal modelling of the lumbar spine to explore functional interactions between back muscle loads and intervertebral disc multiphysics |
| title_full_unstemmed | Musculoskeletal modelling of the lumbar spine to explore functional interactions between back muscle loads and intervertebral disc multiphysics |
| title_short | Musculoskeletal modelling of the lumbar spine to explore functional interactions between back muscle loads and intervertebral disc multiphysics |
| title_sort | musculoskeletal modelling of the lumbar spine to explore functional interactions between back muscle loads and intervertebral disc multiphysics |
| topic | standing night rest Constitutive muscle model Lumbar spine finite element model Intervertebral disc swelling Intervertebral disc-muscle interaction |
| url | http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00111/full |
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