Ketamine Modulates Zic5 Expression via the Notch Signaling Pathway in Neural Crest Induction

Ketamine Modulates Zic5 Expression via the Notch Signaling Pathway in Neural Crest Induction

Ketamine is a potent dissociative anesthetic and the most commonly used illicit drug. Many addicts are women at childbearing age. Although ketamine has been extensively studied as a clinical anesthetic, its effects on embryonic development are poorly understood. Here, we applied the Xenopus model to...

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Bibliographic Details
Main Authors: Yu Shi, Jiejing Li, Chunjiang Chen, Yongwu Xia, Yanxi Li, Pan Zhang, Ying Xu, Tingyu Li, Weihui Zhou, Weihong Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Xenopus
neural crest
ketamine
Notch
Zic5
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00009/full

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