Human Immune Deficiency Virus Serostatus and Associated Factors Among Children of Adult Index Cases in Northern Ethiopia
Medhin Mehari,1 Meresa Gebremedhin Weldu,2 Teklit Angesom,2 Hagos Degefa Hidru,1 Hirut Teame,1 Haftay Gebremedhin,1 Yonas Angaw,1 Embay Amare Alemseged1 1Adigrat University College of Medicine and Health Science, Department of Public Health, Adigrat, Tigrai, Ethiopia; 2Aksum University College of Me...
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2021-06-01
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| Series: | HIV/AIDS: Research and Palliative Care |
| Subjects: | |
| Online Access: | https://www.dovepress.com/human-immune-deficiency-virus-serostatus-and-associated-factors-among--peer-reviewed-fulltext-article-HIV |
| _version_ | 1818722853593284608 |
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| author | Mehari M Weldu MG Angesom T Hidru HD Teame H Gebremedhin H Angaw Y Alemseged EA |
| author_facet | Mehari M Weldu MG Angesom T Hidru HD Teame H Gebremedhin H Angaw Y Alemseged EA |
| author_sort | Mehari M |
| collection | DOAJ |
| description | Medhin Mehari,1 Meresa Gebremedhin Weldu,2 Teklit Angesom,2 Hagos Degefa Hidru,1 Hirut Teame,1 Haftay Gebremedhin,1 Yonas Angaw,1 Embay Amare Alemseged1 1Adigrat University College of Medicine and Health Science, Department of Public Health, Adigrat, Tigrai, Ethiopia; 2Aksum University College of Medicine and Health Science, Department of Public Health, Aksum, Tigrai, EthiopiaCorrespondence: Medhin Mehari Tel +251914194266Email medhinmehari493@gmail.comIntroduction: Children whose parents with human immunodeficiency virus (HIV) and family of index clients are at high risk of HIV infection. Family testing is an efficient and effective way of identifying children’s HIV. The number of children becoming newly infected with HIV remains unacceptably high. This study is to assess human immune deficiency, virus serostatus, and associated factors among children of adult index cases in central Tigrai, Northern Ethiopia, 2019.Methods: An institution-based cross-sectional study design was conducted to select a total of 454 index cases from February 01 to April 30, 2019. Data were collected from adult clients on antiretroviral treatment who have children using administered questionnaires and data extraction from the hospital antiretroviral register. Simple random sampling was used to select the index cases using the medical record number. Binary logistic regression analysis, odds ratio, and 95% confidence interval were used to determine the strength of association between dependent and independent variables. Statistical significance was declared a P-value < 0.05.Results: The prevalence of HIV in children from family index case testing was 8.9% with 95% CI (6.5– 11.6). Female index clients [AOR=0.18, 95% CI: 06-0.55], the age of the child [AOR=0.86, 95% CI: 0.76, 0.97], importance of HIV testing [AOR=5.20, 95% CI: 2.2011.96], and discussion HIV testing [AOR=3.22, 95% CI: 1.5– 16.84]. Participants who did not discuss HIV were 3.2 more likely have HIV positive child than who discussed with family members.Conclusion: The majority of the index clients test their children, but the prevalence rate of HIV in children from family index case testing is high. Strategies should be developed on how to communicate with household members about HIV.Keywords: HIV serostatus, human immunodeficiency virus, HIV index case, HIV in children, antiretroviral therapy, ART, HIV/AIDS |
| first_indexed | 2024-12-17T21:01:14Z |
| format | Article |
| id | doaj.art-2bbcd6616e0043179125ce54eb90f3c9 |
| institution | Directory Open Access Journal |
| issn | 1179-1373 |
| language | English |
| last_indexed | 2024-12-17T21:01:14Z |
| publishDate | 2021-06-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | HIV/AIDS: Research and Palliative Care |
| spelling | doaj.art-2bbcd6616e0043179125ce54eb90f3c92022-12-21T21:32:43ZengDove Medical PressHIV/AIDS: Research and Palliative Care1179-13732021-06-01Volume 1369970766252Human Immune Deficiency Virus Serostatus and Associated Factors Among Children of Adult Index Cases in Northern EthiopiaMehari MWeldu MGAngesom THidru HDTeame HGebremedhin HAngaw YAlemseged EAMedhin Mehari,1 Meresa Gebremedhin Weldu,2 Teklit Angesom,2 Hagos Degefa Hidru,1 Hirut Teame,1 Haftay Gebremedhin,1 Yonas Angaw,1 Embay Amare Alemseged1 1Adigrat University College of Medicine and Health Science, Department of Public Health, Adigrat, Tigrai, Ethiopia; 2Aksum University College of Medicine and Health Science, Department of Public Health, Aksum, Tigrai, EthiopiaCorrespondence: Medhin Mehari Tel +251914194266Email medhinmehari493@gmail.comIntroduction: Children whose parents with human immunodeficiency virus (HIV) and family of index clients are at high risk of HIV infection. Family testing is an efficient and effective way of identifying children’s HIV. The number of children becoming newly infected with HIV remains unacceptably high. This study is to assess human immune deficiency, virus serostatus, and associated factors among children of adult index cases in central Tigrai, Northern Ethiopia, 2019.Methods: An institution-based cross-sectional study design was conducted to select a total of 454 index cases from February 01 to April 30, 2019. Data were collected from adult clients on antiretroviral treatment who have children using administered questionnaires and data extraction from the hospital antiretroviral register. Simple random sampling was used to select the index cases using the medical record number. Binary logistic regression analysis, odds ratio, and 95% confidence interval were used to determine the strength of association between dependent and independent variables. Statistical significance was declared a P-value < 0.05.Results: The prevalence of HIV in children from family index case testing was 8.9% with 95% CI (6.5– 11.6). Female index clients [AOR=0.18, 95% CI: 06-0.55], the age of the child [AOR=0.86, 95% CI: 0.76, 0.97], importance of HIV testing [AOR=5.20, 95% CI: 2.2011.96], and discussion HIV testing [AOR=3.22, 95% CI: 1.5– 16.84]. Participants who did not discuss HIV were 3.2 more likely have HIV positive child than who discussed with family members.Conclusion: The majority of the index clients test their children, but the prevalence rate of HIV in children from family index case testing is high. Strategies should be developed on how to communicate with household members about HIV.Keywords: HIV serostatus, human immunodeficiency virus, HIV index case, HIV in children, antiretroviral therapy, ART, HIV/AIDShttps://www.dovepress.com/human-immune-deficiency-virus-serostatus-and-associated-factors-among--peer-reviewed-fulltext-article-HIVhiv sero-statushuman immunodeficiency virushiv index casehiv in childrenantiretroviral therapyarthiv/aids |
| spellingShingle | Mehari M Weldu MG Angesom T Hidru HD Teame H Gebremedhin H Angaw Y Alemseged EA Human Immune Deficiency Virus Serostatus and Associated Factors Among Children of Adult Index Cases in Northern Ethiopia HIV/AIDS: Research and Palliative Care hiv sero-status human immunodeficiency virus hiv index case hiv in children antiretroviral therapy art hiv/aids |
| title | Human Immune Deficiency Virus Serostatus and Associated Factors Among Children of Adult Index Cases in Northern Ethiopia |
| title_full | Human Immune Deficiency Virus Serostatus and Associated Factors Among Children of Adult Index Cases in Northern Ethiopia |
| title_fullStr | Human Immune Deficiency Virus Serostatus and Associated Factors Among Children of Adult Index Cases in Northern Ethiopia |
| title_full_unstemmed | Human Immune Deficiency Virus Serostatus and Associated Factors Among Children of Adult Index Cases in Northern Ethiopia |
| title_short | Human Immune Deficiency Virus Serostatus and Associated Factors Among Children of Adult Index Cases in Northern Ethiopia |
| title_sort | human immune deficiency virus serostatus and associated factors among children of adult index cases in northern ethiopia |
| topic | hiv sero-status human immunodeficiency virus hiv index case hiv in children antiretroviral therapy art hiv/aids |
| url | https://www.dovepress.com/human-immune-deficiency-virus-serostatus-and-associated-factors-among--peer-reviewed-fulltext-article-HIV |
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