The prevalence and spectrum of mucocutaneous disease in South African people living with HIV and accessing care at a district-level hospital
Background: Although the association between human immunodeficiency virus (HIV) and mucocutaneous diseases has been well studied within South African specialist centres, there is limited data from district-level hospitals. Available data may, therefore, fail to reflect the prevalence and full spectr...
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| Format: | Article |
| Language: | English |
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AOSIS
2020-12-01
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| Series: | Southern African Journal of HIV Medicine |
| Subjects: | |
| Online Access: | https://sajhivmed.org.za/index.php/hivmed/article/view/1154 |
| _version_ | 1817983519180193792 |
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| author | Saskya Claasens Susanna M.H. Kannenberg Henry F. Jordaan Karis Moxley Rhodine Smith Johann de Wet Willem I. Visser |
| author_facet | Saskya Claasens Susanna M.H. Kannenberg Henry F. Jordaan Karis Moxley Rhodine Smith Johann de Wet Willem I. Visser |
| author_sort | Saskya Claasens |
| collection | DOAJ |
| description | Background: Although the association between human immunodeficiency virus (HIV) and mucocutaneous diseases has been well studied within South African specialist centres, there is limited data from district-level hospitals. Available data may, therefore, fail to reflect the prevalence and full spectrum of dermatoses seen in people living with HIV (PLWH).
Objectives: To determine the prevalence and spectrum of dermatoses seen in PLWH.
Method: We conducted a cross-sectional, descriptive study of 970 PLWH (men and women, ≥ 18 years old) accessing care at Karl Bremer Hospital, a district-level hospital located in the Western Cape province, South Africa, between 01 September 2016 and 28 February 2017.
Results: The prevalence of mucocutaneous disease in this sample was 12.7% (95% confidence interval [CI] 0.11–0.15). Non-infectious dermatoses comprised 71.0% of the disorders. Pruritic papular eruption (20.0%) and seborrheic dermatitis (6.0%) were the most common non-infectious dermatoses. Tinea corporis (8.0%) and oral candidiasis (6.0%) were the most prevalent infectious dermatoses. There was no significant association between skin disease category (infectious or non-infectious dermatoses) and patient demographics (gender and ethnicity) or HIV-disease characteristics (CD4+ cell count, viral load and duration of antiretroviral therapy [ART]).
Conclusion: This study provides valuable scientific data on the prevalence and spectrum of mucocutaneous disease in PLWH attending a South African district-level hospital. Prospective studies conducted in other district-level centres across the country are required to determine the lifetime prevalence and spectrum of dermatoses in PLWH in the ART era. |
| first_indexed | 2024-04-13T23:33:09Z |
| format | Article |
| id | doaj.art-2bbde18bbe7e4f64a61ed14dc379789c |
| institution | Directory Open Access Journal |
| issn | 1608-9693 2078-6751 |
| language | English |
| last_indexed | 2024-04-13T23:33:09Z |
| publishDate | 2020-12-01 |
| publisher | AOSIS |
| record_format | Article |
| series | Southern African Journal of HIV Medicine |
| spelling | doaj.art-2bbde18bbe7e4f64a61ed14dc379789c2022-12-22T02:24:49ZengAOSISSouthern African Journal of HIV Medicine1608-96932078-67512020-12-01211e1e710.4102/sajhivmed.v21i1.1154715The prevalence and spectrum of mucocutaneous disease in South African people living with HIV and accessing care at a district-level hospitalSaskya Claasens0Susanna M.H. Kannenberg1Henry F. Jordaan2Karis Moxley3Rhodine Smith4Johann de Wet5Willem I. Visser6Division of Dermatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDivision of Dermatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDivision of Dermatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownResearch Development and Support Division, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDivision of Dermatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa; and, Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDivision of Dermatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownDivision of Dermatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape TownBackground: Although the association between human immunodeficiency virus (HIV) and mucocutaneous diseases has been well studied within South African specialist centres, there is limited data from district-level hospitals. Available data may, therefore, fail to reflect the prevalence and full spectrum of dermatoses seen in people living with HIV (PLWH). Objectives: To determine the prevalence and spectrum of dermatoses seen in PLWH. Method: We conducted a cross-sectional, descriptive study of 970 PLWH (men and women, ≥ 18 years old) accessing care at Karl Bremer Hospital, a district-level hospital located in the Western Cape province, South Africa, between 01 September 2016 and 28 February 2017. Results: The prevalence of mucocutaneous disease in this sample was 12.7% (95% confidence interval [CI] 0.11–0.15). Non-infectious dermatoses comprised 71.0% of the disorders. Pruritic papular eruption (20.0%) and seborrheic dermatitis (6.0%) were the most common non-infectious dermatoses. Tinea corporis (8.0%) and oral candidiasis (6.0%) were the most prevalent infectious dermatoses. There was no significant association between skin disease category (infectious or non-infectious dermatoses) and patient demographics (gender and ethnicity) or HIV-disease characteristics (CD4+ cell count, viral load and duration of antiretroviral therapy [ART]). Conclusion: This study provides valuable scientific data on the prevalence and spectrum of mucocutaneous disease in PLWH attending a South African district-level hospital. Prospective studies conducted in other district-level centres across the country are required to determine the lifetime prevalence and spectrum of dermatoses in PLWH in the ART era.https://sajhivmed.org.za/index.php/hivmed/article/view/1154mucocutaneous diseasehivdistrict-level hospitalsartsouth africa |
| spellingShingle | Saskya Claasens Susanna M.H. Kannenberg Henry F. Jordaan Karis Moxley Rhodine Smith Johann de Wet Willem I. Visser The prevalence and spectrum of mucocutaneous disease in South African people living with HIV and accessing care at a district-level hospital Southern African Journal of HIV Medicine mucocutaneous disease hiv district-level hospitals art south africa |
| title | The prevalence and spectrum of mucocutaneous disease in South African people living with HIV and accessing care at a district-level hospital |
| title_full | The prevalence and spectrum of mucocutaneous disease in South African people living with HIV and accessing care at a district-level hospital |
| title_fullStr | The prevalence and spectrum of mucocutaneous disease in South African people living with HIV and accessing care at a district-level hospital |
| title_full_unstemmed | The prevalence and spectrum of mucocutaneous disease in South African people living with HIV and accessing care at a district-level hospital |
| title_short | The prevalence and spectrum of mucocutaneous disease in South African people living with HIV and accessing care at a district-level hospital |
| title_sort | prevalence and spectrum of mucocutaneous disease in south african people living with hiv and accessing care at a district level hospital |
| topic | mucocutaneous disease hiv district-level hospitals art south africa |
| url | https://sajhivmed.org.za/index.php/hivmed/article/view/1154 |
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