Innovations in acute stroke reperfusion strategies

Vascular neurology is witnessing unprecedented innovations in the management of acute ischemic stroke, especially in reperfusion strategies. The emergence of mechanical thrombectomy with new generation devices has revolutionized the treatment of acute ischemic stroke with large vessel occlusion. The...

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Main Authors: Venugopalan Y Vishnu, M V Padma Srivastava
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2019;volume=22;issue=1;spage=6;epage=12;aulast=Vishnu
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author Venugopalan Y Vishnu
M V Padma Srivastava
author_facet Venugopalan Y Vishnu
M V Padma Srivastava
author_sort Venugopalan Y Vishnu
collection DOAJ
description Vascular neurology is witnessing unprecedented innovations in the management of acute ischemic stroke, especially in reperfusion strategies. The emergence of mechanical thrombectomy with new generation devices has revolutionized the treatment of acute ischemic stroke with large vessel occlusion. The reperfusion strategies are evolving with the extension of the window period for thrombolysis and endovascular therapy through the concept of “tissue clock” in addition to the established “time clock.” The newer generation of thrombolytic drugs like tenecteplase are promising exciting times ahead in acute stroke care. In this “viewpoint,'” the evolution of reperfusion therapy in acute ischemic stroke will be discussed followed by recent innovations in reperfusion strategies.
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spelling doaj.art-2bbef195dfd64a54a9f178985fc81d9b2022-12-22T01:13:15ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492019-01-0122161210.4103/aian.AIAN_263_18Innovations in acute stroke reperfusion strategiesVenugopalan Y VishnuM V Padma SrivastavaVascular neurology is witnessing unprecedented innovations in the management of acute ischemic stroke, especially in reperfusion strategies. The emergence of mechanical thrombectomy with new generation devices has revolutionized the treatment of acute ischemic stroke with large vessel occlusion. The reperfusion strategies are evolving with the extension of the window period for thrombolysis and endovascular therapy through the concept of “tissue clock” in addition to the established “time clock.” The newer generation of thrombolytic drugs like tenecteplase are promising exciting times ahead in acute stroke care. In this “viewpoint,'” the evolution of reperfusion therapy in acute ischemic stroke will be discussed followed by recent innovations in reperfusion strategies.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2019;volume=22;issue=1;spage=6;epage=12;aulast=VishnuAcute stroke therapyischemic strokemagnetic resonance imagingrecombinant tissue plasminogen activatorreperfusion therapytenecteplasethrombectomythrombolytic therapy
spellingShingle Venugopalan Y Vishnu
M V Padma Srivastava
Innovations in acute stroke reperfusion strategies
Annals of Indian Academy of Neurology
Acute stroke therapy
ischemic stroke
magnetic resonance imaging
recombinant tissue plasminogen activator
reperfusion therapy
tenecteplase
thrombectomy
thrombolytic therapy
title Innovations in acute stroke reperfusion strategies
title_full Innovations in acute stroke reperfusion strategies
title_fullStr Innovations in acute stroke reperfusion strategies
title_full_unstemmed Innovations in acute stroke reperfusion strategies
title_short Innovations in acute stroke reperfusion strategies
title_sort innovations in acute stroke reperfusion strategies
topic Acute stroke therapy
ischemic stroke
magnetic resonance imaging
recombinant tissue plasminogen activator
reperfusion therapy
tenecteplase
thrombectomy
thrombolytic therapy
url http://www.annalsofian.org/article.asp?issn=0972-2327;year=2019;volume=22;issue=1;spage=6;epage=12;aulast=Vishnu
work_keys_str_mv AT venugopalanyvishnu innovationsinacutestrokereperfusionstrategies
AT mvpadmasrivastava innovationsinacutestrokereperfusionstrategies