Basic Helix-Loop-Helix Transcription Factors AabHLH2 and AabHLH3 Function Antagonistically With AaMYC2 and Are Negative Regulators in Artemisinin Biosynthesis

Basic Helix-Loop-Helix Transcription Factors AabHLH2 and AabHLH3 Function Antagonistically With AaMYC2 and Are Negative Regulators in Artemisinin Biosynthesis

Plants have evolved sophisticated systems for regulating the biosynthesis of specialized phytochemicals. Artemisinin, which is a sesquiterpene lactone widely used in anti-malaria treatment, is produced by the Artemisia annua L. plant. However, the artemisinin content in A. annua is low and difficult...

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Bibliographic Details
Main Authors: Qian Shen, Huayi Huang, Lihui Xie, Xiaolong Hao, Sadaf-Ilyas Kayani, Hang Liu, Wei Qin, Tiantian Chen, Qifang Pan, Pin Liu, Kexuan Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Plant Science
Subjects:
bHLH
MYC2
transcription regulation
Artemisia annua
artemisinin
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2022.885622/full

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