Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project [version 1; peer review: 2 approved]
In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity and mortality. Village health workers (VHWs) are often the first point of contact with the formal health system, and for patients with febrile illnesses they can provide earl...
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| Médium: | Článek |
| Jazyk: | English |
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Wellcome
2021-03-01
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| Edice: | Wellcome Open Research |
| On-line přístup: | https://wellcomeopenresearch.org/articles/6-64/v1 |
| _version_ | 1830170111968804864 |
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| author | Arjun Chandna Nan Shwe Nwe Htun Thomas J Peto Marco Liverani Tobias Brummaier Koukeo Phommasone Sazid Ibna Zaman Aye Sandar Zaw Elizabeth Batty Naomi Waithira Melissa Richard-Greenblatt Stuart D Blacksell Ladaporn Bodhidatta James J Callery Watcharintorn Fagnark Shayla Islam Sanchai Lertcharoenchoke Mavuto Mukaka Tiengkham Pongvongsa William HK Schilling Janjira Thaipadungpanit Rupam Tripura Arjen M Dondorp Mayfong Mayxay Nicholas J White Francois Nosten Frank Smithuis Elizabeth A Ashley Richard J Maude Nicholas PJ Day Yoel Lubell |
| author_facet | Arjun Chandna Nan Shwe Nwe Htun Thomas J Peto Marco Liverani Tobias Brummaier Koukeo Phommasone Sazid Ibna Zaman Aye Sandar Zaw Elizabeth Batty Naomi Waithira Melissa Richard-Greenblatt Stuart D Blacksell Ladaporn Bodhidatta James J Callery Watcharintorn Fagnark Shayla Islam Sanchai Lertcharoenchoke Mavuto Mukaka Tiengkham Pongvongsa William HK Schilling Janjira Thaipadungpanit Rupam Tripura Arjen M Dondorp Mayfong Mayxay Nicholas J White Francois Nosten Frank Smithuis Elizabeth A Ashley Richard J Maude Nicholas PJ Day Yoel Lubell |
| author_sort | Arjun Chandna |
| collection | DOAJ |
| description | In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity and mortality. Village health workers (VHWs) are often the first point of contact with the formal health system, and for patients with febrile illnesses they can provide early diagnosis and treatment of malaria. However, for the majority of febrile patients, VHWs lack the training, support and resources to provide further care. Consequently, treatable bacterial illnesses are missed, antibiotics are overused and poorly targeted, and patient attendance wanes along with declining malaria. This Open Letter announces the start of a new initiative, the Rural Febrile Illness (RFI) project, the first in a series of projects to be implemented as part of the South and Southeast Asian Community-based Trials Network (SEACTN) research programme. This multi-country, multi-site project will begin in Bangladesh, Cambodia, Lao PDR, and Myanmar and will define the epidemiological baseline of febrile illness in five remote and underserved areas of Asia where malaria endemicity is declining and access to health services is limited. The RFI project aims to determine the incidence, causes and outcomes of febrile illness; understand the opportunities, barriers and appetite for adjustment of the role of VHWs to include management of non-malarial febrile illnesses; and establish a network of community healthcare providers and facilities capable of implementing interventions designed to triage, diagnose and treat patients presenting with febrile illnesses within these communities in the future. |
| first_indexed | 2024-12-17T17:30:12Z |
| format | Article |
| id | doaj.art-2bc2e2a55dda4d1a8cc8b01d66e64cb8 |
| institution | Directory Open Access Journal |
| issn | 2398-502X |
| language | English |
| last_indexed | 2024-12-17T17:30:12Z |
| publishDate | 2021-03-01 |
| publisher | Wellcome |
| record_format | Article |
| series | Wellcome Open Research |
| spelling | doaj.art-2bc2e2a55dda4d1a8cc8b01d66e64cb82022-12-21T21:39:30ZengWellcomeWellcome Open Research2398-502X2021-03-01610.12688/wellcomeopenres.16393.118033Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project [version 1; peer review: 2 approved]Arjun Chandna0Nan Shwe Nwe Htun1Thomas J Peto2Marco Liverani3Tobias Brummaier4Koukeo Phommasone5Sazid Ibna Zaman6Aye Sandar Zaw7Elizabeth Batty8Naomi Waithira9Melissa Richard-Greenblatt10Stuart D Blacksell11Ladaporn Bodhidatta12James J Callery13Watcharintorn Fagnark14Shayla Islam15Sanchai Lertcharoenchoke16Mavuto Mukaka17Tiengkham Pongvongsa18William HK Schilling19Janjira Thaipadungpanit20Rupam Tripura21Arjen M Dondorp22Mayfong Mayxay23Nicholas J White24Francois Nosten25Frank Smithuis26Elizabeth A Ashley27Richard J Maude28Nicholas PJ Day29Yoel Lubell30Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, ThailandCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKDepartment of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UKCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKLao-Oxford-Mahosot Hospital Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao People's Democratic RepublicCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKMyanmar Oxford Clinical Research Unit, Yangon, MyanmarCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKUniversity of Pennsylvania, Pennsylvania, USACentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, ThailandMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, ThailandMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, ThailandHealth Nutrition and Population Programme, BRAC, Dhaka, BangladeshMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, ThailandCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKSavannakhet Provincial Health Department, Savannakhet, Lao People's Democratic RepublicCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, ThailandCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKLao-Oxford-Mahosot Hospital Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao People's Democratic RepublicCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, ThailandCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKIn rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity and mortality. Village health workers (VHWs) are often the first point of contact with the formal health system, and for patients with febrile illnesses they can provide early diagnosis and treatment of malaria. However, for the majority of febrile patients, VHWs lack the training, support and resources to provide further care. Consequently, treatable bacterial illnesses are missed, antibiotics are overused and poorly targeted, and patient attendance wanes along with declining malaria. This Open Letter announces the start of a new initiative, the Rural Febrile Illness (RFI) project, the first in a series of projects to be implemented as part of the South and Southeast Asian Community-based Trials Network (SEACTN) research programme. This multi-country, multi-site project will begin in Bangladesh, Cambodia, Lao PDR, and Myanmar and will define the epidemiological baseline of febrile illness in five remote and underserved areas of Asia where malaria endemicity is declining and access to health services is limited. The RFI project aims to determine the incidence, causes and outcomes of febrile illness; understand the opportunities, barriers and appetite for adjustment of the role of VHWs to include management of non-malarial febrile illnesses; and establish a network of community healthcare providers and facilities capable of implementing interventions designed to triage, diagnose and treat patients presenting with febrile illnesses within these communities in the future.https://wellcomeopenresearch.org/articles/6-64/v1 |
| spellingShingle | Arjun Chandna Nan Shwe Nwe Htun Thomas J Peto Marco Liverani Tobias Brummaier Koukeo Phommasone Sazid Ibna Zaman Aye Sandar Zaw Elizabeth Batty Naomi Waithira Melissa Richard-Greenblatt Stuart D Blacksell Ladaporn Bodhidatta James J Callery Watcharintorn Fagnark Shayla Islam Sanchai Lertcharoenchoke Mavuto Mukaka Tiengkham Pongvongsa William HK Schilling Janjira Thaipadungpanit Rupam Tripura Arjen M Dondorp Mayfong Mayxay Nicholas J White Francois Nosten Frank Smithuis Elizabeth A Ashley Richard J Maude Nicholas PJ Day Yoel Lubell Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project [version 1; peer review: 2 approved] Wellcome Open Research |
| title | Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project [version 1; peer review: 2 approved] |
| title_full | Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project [version 1; peer review: 2 approved] |
| title_fullStr | Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project [version 1; peer review: 2 approved] |
| title_full_unstemmed | Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project [version 1; peer review: 2 approved] |
| title_short | Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project [version 1; peer review: 2 approved] |
| title_sort | defining the burden of febrile illness in rural south and southeast asia an open letter to announce the launch of the rural febrile illness project version 1 peer review 2 approved |
| url | https://wellcomeopenresearch.org/articles/6-64/v1 |
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