Denosumab use in osteogenesis imperfecta: an update on therapeutic approaches

Denosumab use in osteogenesis imperfecta: an update on therapeutic approaches

Osteogenesis imperfecta (OI) is an inherited skeletal disorder that leads to bone fragility and multiple fractures. Given advances in the genetic understanding of existing phenotypes and newly discovered mutations, therapeutic management of OI has become challenging. Denosumab, a monoclonal antibody...

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Bibliographic Details
Main Authors: Fatma Majdoub, Hanene Lassoued Ferjani, Dorra Ben Nessib, Dhia Kaffel, Kaouther Maatallah, Wafa Hamdi
Format: Article
Language:English
Published: Korean Society of Pediatric Endocrinology 2023-06-01
Series:Annals of Pediatric Endocrinology & Metabolism
Subjects:
osteogenesis imperfecta
denosumab
rank ligand
rank
Online Access:http://e-apem.org/upload/pdf/apem-2346058-029.pdf

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