Intravenous administration of L-tryptophan stimulates gastrointestinal hormones and melatonin secretions: study on beef cattle
This study aimed to determine the effective dose of intravenous administration of L-tryptophan (L-T) on gastrointestinal hormones (GIH) secretions and melatonin using Hanwoo cattle. Three steers (362 ± 23 kg) fitted with indwelling jugular...
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| Format: | Article |
| Language: | English |
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Korean Society of Animal Sciences and Technology
2019-07-01
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| Series: | Journal of Animal Science and Technology |
| Subjects: | |
| Online Access: | http://www.ejast.org/archive/view_article?pid=jast-61-4-239 |
| _version_ | 1818539083147771904 |
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| author | Sang-Bum Lee Kyung-Won Lee Tao Wang Jae-Sung Lee U-Suk Jung Jalil Ghassemi Nejad Young-Kyoon Oh Youl-Chang Baek Kyoung Hoon Kim Hong-Gu Lee |
| author_facet | Sang-Bum Lee Kyung-Won Lee Tao Wang Jae-Sung Lee U-Suk Jung Jalil Ghassemi Nejad Young-Kyoon Oh Youl-Chang Baek Kyoung Hoon Kim Hong-Gu Lee |
| author_sort | Sang-Bum Lee |
| collection | DOAJ |
| description | This study aimed to determine the effective dose of intravenous administration of
L-tryptophan (L-T) on gastrointestinal hormones (GIH) secretions and melatonin
using Hanwoo cattle. Three steers (362 ± 23 kg) fitted with indwelling
jugular vein catheters were assigned in a 3 × 3 Latin square design.
Treatments were intravenous administration of saline (control), 28.9 mg L-T/kg
body weight (BW; low) and 57.8 mg L-T/kg BW (high) L-T for 1 day with 7 days of
adaptation. Samples were collected after adaptation period at −60, 0, 30,
60, 90, 120, 150, 180, 240, and 300 min of sampling day. The levels of serum
cholecystokinin (CCK) and secretin were higher (p <
0.05) in the high L-T group than those in the other groups. Serum Melatonin
(MEL) levels were increased upon L-T administration (p <
0.05) in the high L-T group. Taken together, the effective dose of L-T
administration was defined at 57.8 mg L-T/kg BW in order to stimulate increase
of GIH and MEL. |
| first_indexed | 2024-12-11T21:37:22Z |
| format | Article |
| id | doaj.art-2bc73ef23adb42d1b91aeedc9bfd5992 |
| institution | Directory Open Access Journal |
| issn | 2672-0191 2055-0391 |
| language | English |
| last_indexed | 2024-12-11T21:37:22Z |
| publishDate | 2019-07-01 |
| publisher | Korean Society of Animal Sciences and Technology |
| record_format | Article |
| series | Journal of Animal Science and Technology |
| spelling | doaj.art-2bc73ef23adb42d1b91aeedc9bfd59922022-12-22T00:49:57ZengKorean Society of Animal Sciences and TechnologyJournal of Animal Science and Technology2672-01912055-03912019-07-0161423924410.5187/jast.2019.61.4.239jast-61-4-239Intravenous administration of L-tryptophan stimulates gastrointestinal hormones and melatonin secretions: study on beef cattleSang-Bum Lee0Kyung-Won Lee1Tao Wang2Jae-Sung Lee3U-Suk Jung4Jalil Ghassemi Nejad5Young-Kyoon Oh6Youl-Chang Baek7Kyoung Hoon Kim8Hong-Gu Lee9Department of Animal Science and Technology, College of Animal Bioscience and Technology, Konkuk University, Seoul 05029, KoreaLife Science Technology, Inc., Seoul 06134, KoreaDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Jilin Agricultural University, Jilin 130118, ChinaDepartment of Animal Science and Technology, College of Animal Bioscience and Technology, Konkuk University, Seoul 05029, KoreaDepartment of Animal Science and Technology, College of Animal Bioscience and Technology, Konkuk University, Seoul 05029, KoreaDepartment of Animal Science and Technology, College of Animal Bioscience and Technology, Konkuk University, Seoul 05029, KoreaDepartment of Nutrition and Physiology, National Institute of Animal Science, RDA, JeonJu 55365, KoreaDepartment of Nutrition and Physiology, National Institute of Animal Science, RDA, JeonJu 55365, KoreaGraduate School of International Agricultural Technology, Pyeongchang Campus, Seoul National University, Pyeongchang 25354, KoreaDepartment of Animal Science and Technology, College of Animal Bioscience and Technology, Konkuk University, Seoul 05029, KoreaThis study aimed to determine the effective dose of intravenous administration of L-tryptophan (L-T) on gastrointestinal hormones (GIH) secretions and melatonin using Hanwoo cattle. Three steers (362 ± 23 kg) fitted with indwelling jugular vein catheters were assigned in a 3 × 3 Latin square design. Treatments were intravenous administration of saline (control), 28.9 mg L-T/kg body weight (BW; low) and 57.8 mg L-T/kg BW (high) L-T for 1 day with 7 days of adaptation. Samples were collected after adaptation period at −60, 0, 30, 60, 90, 120, 150, 180, 240, and 300 min of sampling day. The levels of serum cholecystokinin (CCK) and secretin were higher (p < 0.05) in the high L-T group than those in the other groups. Serum Melatonin (MEL) levels were increased upon L-T administration (p < 0.05) in the high L-T group. Taken together, the effective dose of L-T administration was defined at 57.8 mg L-T/kg BW in order to stimulate increase of GIH and MEL.http://www.ejast.org/archive/view_article?pid=jast-61-4-239amino acidcholecystokininghrelinmelatoninl-tryptophan |
| spellingShingle | Sang-Bum Lee Kyung-Won Lee Tao Wang Jae-Sung Lee U-Suk Jung Jalil Ghassemi Nejad Young-Kyoon Oh Youl-Chang Baek Kyoung Hoon Kim Hong-Gu Lee Intravenous administration of L-tryptophan stimulates gastrointestinal hormones and melatonin secretions: study on beef cattle Journal of Animal Science and Technology amino acid cholecystokinin ghrelin melatonin l-tryptophan |
| title | Intravenous administration of L-tryptophan stimulates
gastrointestinal hormones and melatonin secretions: study on beef
cattle |
| title_full | Intravenous administration of L-tryptophan stimulates
gastrointestinal hormones and melatonin secretions: study on beef
cattle |
| title_fullStr | Intravenous administration of L-tryptophan stimulates
gastrointestinal hormones and melatonin secretions: study on beef
cattle |
| title_full_unstemmed | Intravenous administration of L-tryptophan stimulates
gastrointestinal hormones and melatonin secretions: study on beef
cattle |
| title_short | Intravenous administration of L-tryptophan stimulates
gastrointestinal hormones and melatonin secretions: study on beef
cattle |
| title_sort | intravenous administration of l tryptophan stimulates gastrointestinal hormones and melatonin secretions study on beef cattle |
| topic | amino acid cholecystokinin ghrelin melatonin l-tryptophan |
| url | http://www.ejast.org/archive/view_article?pid=jast-61-4-239 |
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