Long-Term Outcomes of Pyeloplasty in Children with Poorly Functioning Kidneys
Objective: This study aimed to determine the efficacy and long-term outcomes of pyeloplasty in children with poorly functioning kidneys. Materials and Methods: Twenty-six patient charts were reviewed who underwent pyeloplasty with poorly functioning kidneys from 2008 to 2020. Patients were divided i...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2023-12-01
|
| Series: | Journal of Urological Surgery |
| Subjects: | |
| Online Access: |
http://jurolsurgery.org/archives/archive-detail/article-preview/long-term-outcomes-of-pyeloplasty-in-children-with/62781
|
| _version_ | 1797390194035392512 |
|---|---|
| author | Ayşe Başak Uçan Gökben Yaslı Müge Şahin Özkan Okur Arzu Şencan |
| author_facet | Ayşe Başak Uçan Gökben Yaslı Müge Şahin Özkan Okur Arzu Şencan |
| author_sort | Ayşe Başak Uçan |
| collection | DOAJ |
| description | Objective: This study aimed to determine the efficacy and long-term outcomes of pyeloplasty in children with poorly functioning kidneys. Materials and Methods: Twenty-six patient charts were reviewed who underwent pyeloplasty with poorly functioning kidneys from 2008 to 2020. Patients were divided into two groups based on DRF; Group 1: 0-10%, and Group 2: between 10-30%. Patient demographics, preoperative and postoperative anteroposterior diameter (APD), parenchymal renal thickness (PT) ratio, and differential renal function (DF) were analyzed to confirm the postoperative benefits and potential predictors of renal functional recoverability. The parameters of patients younger than one year of age were also compared to those of older patients. Results: The renal function of 12 of 26 patients’ was <10% (mean DF 4.9±3.8%) (Group I). The DF of the other 14 patients was between 10-30% (mean DF 22.6%) (Group II). Sex, age at operation, antenatal diagnosis, preoperative APD, DF, PT ratio, and UTI were also evaluated using multivariate analysis, but none of the parameters were found to be predictable for renal function improvement (p>0.0001). The postoperative PT ratio and postoperative DF were increased in Group II, but not in Group I. DF and PT ratios also improved in Group II in patients younger than 1 year of age (p=0.014, p=0.032 respectively). Hypertension was detected in 5 patients (41.6%) during follow-up in Group I. Conclusion: Pyeloplasty is recommended considering parenchymal and DF recovery in patients younger than 1 year of age with a DF of 10-30%. However, in patients with <10%, parenchymal or DF improvement was unsatisfactory, even in the late renogram. |
| first_indexed | 2024-03-08T23:08:15Z |
| format | Article |
| id | doaj.art-2bc741415a10499f97fa43ccb848aa4e |
| institution | Directory Open Access Journal |
| issn | 2148-9580 |
| language | English |
| last_indexed | 2024-03-08T23:08:15Z |
| publishDate | 2023-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Journal of Urological Surgery |
| spelling | doaj.art-2bc741415a10499f97fa43ccb848aa4e2023-12-15T10:16:31ZengGalenos YayineviJournal of Urological Surgery2148-95802023-12-0110430130610.4274/jus.galenos.2023.2023-8-613049054Long-Term Outcomes of Pyeloplasty in Children with Poorly Functioning KidneysAyşe Başak Uçan0Gökben Yaslı1Müge Şahin2Özkan Okur3Arzu Şencan4 University of Health Sciences Turkiye, Dr. Behçet Uz Training and Research Hospital, Department of Pediatric Surgery, İzmir, Turkiye İzmir Provincial Directorate of Health Non-Communicable Diseases Unit, İzmir, Turkiye University of Health Sciences Turkiye, Dr. Behçet Uz Training and Research Hospital, Department of Pediatric Surgery, İzmir, Turkiye University of Health Sciences Turkiye, Dr. Behçet Uz Training and Research Hospital, Department of Pediatric Surgery, İzmir, Turkiye University of Health Sciences Turkiye, İzmir Faculty of Medicine, Dr. Behçet Uz Children’s Hospital, Department of Pediatric Surgery, İzmir, Turkiye Objective: This study aimed to determine the efficacy and long-term outcomes of pyeloplasty in children with poorly functioning kidneys. Materials and Methods: Twenty-six patient charts were reviewed who underwent pyeloplasty with poorly functioning kidneys from 2008 to 2020. Patients were divided into two groups based on DRF; Group 1: 0-10%, and Group 2: between 10-30%. Patient demographics, preoperative and postoperative anteroposterior diameter (APD), parenchymal renal thickness (PT) ratio, and differential renal function (DF) were analyzed to confirm the postoperative benefits and potential predictors of renal functional recoverability. The parameters of patients younger than one year of age were also compared to those of older patients. Results: The renal function of 12 of 26 patients’ was <10% (mean DF 4.9±3.8%) (Group I). The DF of the other 14 patients was between 10-30% (mean DF 22.6%) (Group II). Sex, age at operation, antenatal diagnosis, preoperative APD, DF, PT ratio, and UTI were also evaluated using multivariate analysis, but none of the parameters were found to be predictable for renal function improvement (p>0.0001). The postoperative PT ratio and postoperative DF were increased in Group II, but not in Group I. DF and PT ratios also improved in Group II in patients younger than 1 year of age (p=0.014, p=0.032 respectively). Hypertension was detected in 5 patients (41.6%) during follow-up in Group I. Conclusion: Pyeloplasty is recommended considering parenchymal and DF recovery in patients younger than 1 year of age with a DF of 10-30%. However, in patients with <10%, parenchymal or DF improvement was unsatisfactory, even in the late renogram. http://jurolsurgery.org/archives/archive-detail/article-preview/long-term-outcomes-of-pyeloplasty-in-children-with/62781 differential renal functionpoorly functioning kidneyparenchymal renal thicknesspyeloplastyureteropelvic junction obstruction |
| spellingShingle | Ayşe Başak Uçan Gökben Yaslı Müge Şahin Özkan Okur Arzu Şencan Long-Term Outcomes of Pyeloplasty in Children with Poorly Functioning Kidneys Journal of Urological Surgery differential renal function poorly functioning kidney parenchymal renal thickness pyeloplasty ureteropelvic junction obstruction |
| title | Long-Term Outcomes of Pyeloplasty in Children with Poorly Functioning Kidneys |
| title_full | Long-Term Outcomes of Pyeloplasty in Children with Poorly Functioning Kidneys |
| title_fullStr | Long-Term Outcomes of Pyeloplasty in Children with Poorly Functioning Kidneys |
| title_full_unstemmed | Long-Term Outcomes of Pyeloplasty in Children with Poorly Functioning Kidneys |
| title_short | Long-Term Outcomes of Pyeloplasty in Children with Poorly Functioning Kidneys |
| title_sort | long term outcomes of pyeloplasty in children with poorly functioning kidneys |
| topic | differential renal function poorly functioning kidney parenchymal renal thickness pyeloplasty ureteropelvic junction obstruction |
| url |
http://jurolsurgery.org/archives/archive-detail/article-preview/long-term-outcomes-of-pyeloplasty-in-children-with/62781
|
| work_keys_str_mv | AT aysebasakucan longtermoutcomesofpyeloplastyinchildrenwithpoorlyfunctioningkidneys AT gokbenyaslı longtermoutcomesofpyeloplastyinchildrenwithpoorlyfunctioningkidneys AT mugesahin longtermoutcomesofpyeloplastyinchildrenwithpoorlyfunctioningkidneys AT ozkanokur longtermoutcomesofpyeloplastyinchildrenwithpoorlyfunctioningkidneys AT arzusencan longtermoutcomesofpyeloplastyinchildrenwithpoorlyfunctioningkidneys |