Mechanism of action of the bile acid receptor TGR5 in obesity

Mechanism of action of the bile acid receptor TGR5 in obesity

G protein-coupled receptors (GPCRs) are a large family of membrane protein receptors, and Takeda G protein-coupled receptor 5 (TGR5) is a member of this family. As a membrane receptor, TGR5 is widely distributed in different parts of the human body and plays a vital role in regulating metabolism, in...

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Bibliographic Details
Main Authors: Weijun Lun, Qihao Yan, Xinghua Guo, Minchuan Zhou, Yan Bai, Jincan He, Hua Cao, Qishi Che, Jiao Guo, Zhengquan Su
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Obesity
TGR5
Bile acids
Ligand
Appetite
Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523004343

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