Hepatitis C Infection: Current Approach
Hepatitis C virus (HCV) associates acute and chronic liver injury, cirrhosis, and hepatocellular carcinoma, and infects an estimated 170 to 350 million people worldwide. After the identification of the virus in 1989, substantial advances occured over the last years in the fields of diagnosis, treatm...
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| Format: | Article |
| Language: | English |
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Bilimsel Tip Yayinevi
2005-12-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
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| Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2005-10-4-155-162.pdf |
| _version_ | 1797914866542968832 |
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| author | Reşat ÖZARAS |
| author_facet | Reşat ÖZARAS |
| author_sort | Reşat ÖZARAS |
| collection | DOAJ |
| description | Hepatitis C virus (HCV) associates acute and chronic liver injury, cirrhosis, and hepatocellular carcinoma, and infects an estimated 170 to 350 million people worldwide. After the identification of the virus in 1989, substantial advances occured over the last years in the fields of diagnosis, treatment, and prevention. After recognising the role of transmission via infected blood, routine screening for anti-HCV decreased the transmission by this route significantly. Molecular methods improved detection and quantitation of the virus and thus led to easy recognition of the virus and monitoring the response to the treatment. Limited response yielded from interferon (IFN) treatment, improved after combination treatment with ribavirin and giving long acting pegylated IFN. The studies did not result in an effective vaccine. Since the current therapies can not provide a solution in nearly half of the patients, new options are needed. |
| first_indexed | 2024-04-10T12:32:48Z |
| format | Article |
| id | doaj.art-2bcc1b78ab68413fb2e5acc6c2cc3d63 |
| institution | Directory Open Access Journal |
| issn | 1300-932X 1300-932X |
| language | English |
| last_indexed | 2024-04-10T12:32:48Z |
| publishDate | 2005-12-01 |
| publisher | Bilimsel Tip Yayinevi |
| record_format | Article |
| series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| spelling | doaj.art-2bcc1b78ab68413fb2e5acc6c2cc3d632023-02-15T16:14:49ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2005-12-01104155162Hepatitis C Infection: Current ApproachReşat ÖZARAS0İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İSTANBULHepatitis C virus (HCV) associates acute and chronic liver injury, cirrhosis, and hepatocellular carcinoma, and infects an estimated 170 to 350 million people worldwide. After the identification of the virus in 1989, substantial advances occured over the last years in the fields of diagnosis, treatment, and prevention. After recognising the role of transmission via infected blood, routine screening for anti-HCV decreased the transmission by this route significantly. Molecular methods improved detection and quantitation of the virus and thus led to easy recognition of the virus and monitoring the response to the treatment. Limited response yielded from interferon (IFN) treatment, improved after combination treatment with ribavirin and giving long acting pegylated IFN. The studies did not result in an effective vaccine. Since the current therapies can not provide a solution in nearly half of the patients, new options are needed.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2005-10-4-155-162.pdfHepatitis CChronicEpidemiologyDiagnosisTreatmentInterferon |
| spellingShingle | Reşat ÖZARAS Hepatitis C Infection: Current Approach Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Hepatitis C Chronic Epidemiology Diagnosis Treatment Interferon |
| title | Hepatitis C Infection: Current Approach |
| title_full | Hepatitis C Infection: Current Approach |
| title_fullStr | Hepatitis C Infection: Current Approach |
| title_full_unstemmed | Hepatitis C Infection: Current Approach |
| title_short | Hepatitis C Infection: Current Approach |
| title_sort | hepatitis c infection current approach |
| topic | Hepatitis C Chronic Epidemiology Diagnosis Treatment Interferon |
| url | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2005-10-4-155-162.pdf |
| work_keys_str_mv | AT resatozaras hepatitiscinfectioncurrentapproach |