Synthetic Cationic Peptide IDR-1002 and Human Cathelicidin LL37 Modulate the Cell Innate Response but Differentially Impact PRRSV Replication in vitro

Synthetic Cationic Peptide IDR-1002 and Human Cathelicidin LL37 Modulate the Cell Innate Response but Differentially Impact PRRSV Replication in vitro

Host defense peptides (HDPs) show both antimicrobial and immunomodulatory properties making them important mediators of the host immune system. In humans but also in pigs many HDPs have been identified and important families such as cathelicidins and defensins have been established. In our study, we...

Полное описание

Библиографические подробности
Главные авторы:	Benoît Levast, Daniel Hogan, Jill van Kessel, Stacy Strom, Stew Walker, Jianzhong Zhu, François Meurens, Volker Gerdts
Формат:	Статья
Язык:	English
Опубликовано:	Frontiers Media S.A. 2019-07-01
Серии:	Frontiers in Veterinary Science
Предметы:	PRRSV porcine alveolar macrophages host defense peptides poly(I:C) adjuvant
Online-ссылка:	https://www.frontiersin.org/article/10.3389/fvets.2019.00233/full

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