Leiomyosarcoma of the great saphenous vein

A 56-year-old male patient presented with a complaint of two painful, hard, palpable nodules in the right lower limb. A Doppler ultrasound scan revealed the presence of nodules, likely to be neoplastic. Computed angiography showed two solid hypervascular nodules in the right great saphenous vein, fe...

Full description

Bibliographic Details
Main Authors: Alexandre Campos Moraes Amato, Ana Júlia de Deus Silva, Ricardo Virgínio dos Santos, Salvador José de Toledo Arruda Amato
Format: Article
Language:English
Published: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2015-06-01
Series:Jornal Vascular Brasileiro
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492015000200186&lng=en&tlng=en
_version_ 1819230756542611456
author Alexandre Campos Moraes Amato
Ana Júlia de Deus Silva
Ricardo Virgínio dos Santos
Salvador José de Toledo Arruda Amato
author_facet Alexandre Campos Moraes Amato
Ana Júlia de Deus Silva
Ricardo Virgínio dos Santos
Salvador José de Toledo Arruda Amato
author_sort Alexandre Campos Moraes Amato
collection DOAJ
description A 56-year-old male patient presented with a complaint of two painful, hard, palpable nodules in the right lower limb. A Doppler ultrasound scan revealed the presence of nodules, likely to be neoplastic. Computed angiography showed two solid hypervascular nodules in the right great saphenous vein, fed by branches of the posterior tibial artery. Embolization of the nodules using surgical cyanoacrylate was performed, followed by an excisional biopsy. Anatomical pathology and immunohistochemical analysis identified the nodule as a high-grade leiomyosarcoma, characterized by ten mitotic figures per ten high-power fields, necrosis and cell pleomorphism. Immunohistochemical analysis results were positive for caldesmon and desmin labeling. A second surgical procedure was performed to enlarge the free margins.
first_indexed 2024-12-23T11:34:08Z
format Article
id doaj.art-2bd3f53b94fc46ada0afd681152b5c90
institution Directory Open Access Journal
issn 1677-7301
language English
last_indexed 2024-12-23T11:34:08Z
publishDate 2015-06-01
publisher Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
record_format Article
series Jornal Vascular Brasileiro
spelling doaj.art-2bd3f53b94fc46ada0afd681152b5c902022-12-21T17:48:43ZengSociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)Jornal Vascular Brasileiro1677-73012015-06-0114218618810.1590/1677-5449.0077S1677-54492015000200186Leiomyosarcoma of the great saphenous veinAlexandre Campos Moraes AmatoAna Júlia de Deus SilvaRicardo Virgínio dos SantosSalvador José de Toledo Arruda AmatoA 56-year-old male patient presented with a complaint of two painful, hard, palpable nodules in the right lower limb. A Doppler ultrasound scan revealed the presence of nodules, likely to be neoplastic. Computed angiography showed two solid hypervascular nodules in the right great saphenous vein, fed by branches of the posterior tibial artery. Embolization of the nodules using surgical cyanoacrylate was performed, followed by an excisional biopsy. Anatomical pathology and immunohistochemical analysis identified the nodule as a high-grade leiomyosarcoma, characterized by ten mitotic figures per ten high-power fields, necrosis and cell pleomorphism. Immunohistochemical analysis results were positive for caldesmon and desmin labeling. A second surgical procedure was performed to enlarge the free margins.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492015000200186&lng=en&tlng=enneoplasiasneoplasias de tecido vascularvasos sanguíneos
spellingShingle Alexandre Campos Moraes Amato
Ana Júlia de Deus Silva
Ricardo Virgínio dos Santos
Salvador José de Toledo Arruda Amato
Leiomyosarcoma of the great saphenous vein
Jornal Vascular Brasileiro
neoplasias
neoplasias de tecido vascular
vasos sanguíneos
title Leiomyosarcoma of the great saphenous vein
title_full Leiomyosarcoma of the great saphenous vein
title_fullStr Leiomyosarcoma of the great saphenous vein
title_full_unstemmed Leiomyosarcoma of the great saphenous vein
title_short Leiomyosarcoma of the great saphenous vein
title_sort leiomyosarcoma of the great saphenous vein
topic neoplasias
neoplasias de tecido vascular
vasos sanguíneos
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492015000200186&lng=en&tlng=en
work_keys_str_mv AT alexandrecamposmoraesamato leiomyosarcomaofthegreatsaphenousvein
AT anajuliadedeussilva leiomyosarcomaofthegreatsaphenousvein
AT ricardovirginiodossantos leiomyosarcomaofthegreatsaphenousvein
AT salvadorjosedetoledoarrudaamato leiomyosarcomaofthegreatsaphenousvein