Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons.

Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons.

Following injury, dorsal root ganglion (DRG) neurons undergo transcriptional changes so as to adopt phenotypic changes that promote cell survival and axonal regeneration. Here we used a microarray approach to profile changes in a population of small noncoding RNAs known as microRNAs (miRNAs) in the...

Full description

Bibliographic Details
Main Authors:	Iain T Strickland, Louise Richards, Fiona E Holmes, David Wynick, James B Uney, Liang-Fong Wong
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3154476?pdf=render

Similar Items

Selective loss of slow and enhancement of fast Na+currents in cutaneous afferent dorsal root ganglion neurones following axotomy
by: Marco A. Rizzo, et al.
Published: (1995-04-01)

Effects of regenerative peripheral nerve interface on dorsal root ganglia neurons following peripheral axotomy
by: Zheng Wang, et al.
Published: (2022-09-01)

Retinal glia promote dorsal root ganglion axon regeneration.
by: Barbara Lorber, et al.
Published: (2015-01-01)

Dorsal root ganglion neurons recapitulate the traumatic axonal injury of CNS neurons in response to a rapid stretch in vitro
by: Alexandra A. Adams, et al.
Published: (2023-03-01)

Silencing the enhancer of zeste homologue 2, Ezh2, represses axon regeneration of dorsal root ganglion neurons
by: Ting-Ting Guo, et al.
Published: (2022-01-01)

Unraveling Axon Guidance during Axotomy and Regeneration
by: Miguel E. Domínguez-Romero, et al.
Published: (2021-08-01)

The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons
by: Douglas M. Lopes, et al.
Published: (2017-09-01)

Immortalized Dorsal Root Ganglion Neuron Cell Lines
by: Rainer Viktor Haberberger, et al.
Published: (2020-06-01)

Enhanced axon outgrowth of spinal motor neurons in co-culturing with dorsal root ganglions antagonizes the growth inhibitory environment
by: Zi-Xing Xu, et al.
Published: (2024-03-01)

Transcriptional regulatory network during axonal regeneration of dorsal root ganglion neurons: laser-capture microdissection and deep sequencing
by: Li-Li Zhao, et al.
Published: (2023-01-01)

Profile of dorsal root ganglion neurons: study of oxytocin expression
by: Taisei Noguri, et al.
Published: (2022-05-01)

Palmitoylethanolamide Mitigates Paclitaxel Toxicity in Primary Dorsal Root Ganglion Neurons
by: Amira Elfarnawany, et al.
Published: (2022-12-01)

Functional Expression of Piezo1 in Dorsal Root Ganglion (DRG) Neurons
by: Jueun Roh, et al.
Published: (2020-05-01)

Caldendrin represses neurite regeneration and growth in dorsal root ganglion neurons
by: Josue A. Lopez, et al.
Published: (2023-02-01)

Voltage-gated Na+ currents in human dorsal root ganglion neurons
by: Xiulin Zhang, et al.
Published: (2017-05-01)

Single-nucleus transcriptomic analysis of human dorsal root ganglion neurons
by: Minh Q Nguyen, et al.
Published: (2021-11-01)

Shared nociceptive dorsal root ganglion neurons participating in acupoint sensitization
by: Wanrong Li, et al.
Published: (2022-08-01)

Cisplatin induced Mitochondrial DNA damage in dorsal root ganglion neurons
by: Jewel L. Podratz, et al.
Published: (2011-03-01)

Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets
by: Moeko Kudo, et al.
Published: (2021-12-01)

Axotomy Induces Drp1-Dependent Fragmentation of Axonal Mitochondria
by: Joseph Kedra, et al.
Published: (2021-06-01)

Cdk5 Phosphorylation of STAT3 in Dorsal Root Ganglion Neurons Is Involved in Promoting Axonal Regeneration After Peripheral Nerve Injury
by: Jinyeon Hwang, et al.
Published: (2020-05-01)

Calcium in Neuronal and Glial Response to Axotomy
by: Andrey Khaitin
Published: (2021-12-01)

Microglial dynamics after axotomy-induced retinal ganglion cell death
by: Francisco M. Nadal-Nicolás, et al.
Published: (2017-11-01)

Protocol for the isolation and culture of mouse dorsal root ganglion neurons for imaging applications
by: Patrick R. Smith, et al.
Published: (2023-12-01)

Rabies virus infection of cultured adult mouse dorsal root ganglion neurons
by: Jaime Castellanos, et al.
Published: (1996-10-01)

Hypoxic stress enhances extension and branching of dorsal root ganglion neuronal outgrowth
by: Junxuan Ma, et al.
Published: (2020-06-01)

Characterization of Na+ and Ca2+ channels in zebrafish dorsal root ganglion neurons.
by: Yu-Jin Won, et al.
Published: (2012-01-01)

An integrated cell isolation and purification method for rat dorsal root ganglion neurons
by: Huaishuang Shen, et al.
Published: (2019-07-01)

Axotomy increases NADPH-diaphorase activity in the dorsal root ganglia and lumbar spinal cord of the turtle Trachemys dorbigni
by: W.A. Partata, et al.
Published: (1999-04-01)

DORSAL ROOT GANGLION NEURONS FROM A HUNTINGTON’S DISEASE MOUSE MODEL SHOW DIFFERENCES IN THEIR CALCIUM RESPONSE TO AXONAL INJURY BY LASER INDUCED SHOCKWAVE.
by: Veronica Gomez Godinez, et al.
Published: (2023-10-01)

Mechanisms of Action of Dorsal Root Ganglion Stimulation
by: Alaa Abd-Elsayed, et al.
Published: (2024-03-01)

Platinum-Based Drugs Cause Mitochondrial Dysfunction in Cultured Dorsal Root Ganglion Neurons
by: Markus Leo, et al.
Published: (2020-11-01)

Ionic basis of a mechanotransduction current in adult rat dorsal root ganglion neurons
by: McCarter Gordon C, et al.
Published: (2006-08-01)

Enhanced excitability of small dorsal root ganglion neurons in rats with bone cancer pain
by: Zheng Qin, et al.
Published: (2012-04-01)

Correction: Citral Sensing by Transient Receptor Potential Channels in Dorsal Root Ganglion Neurons.
by: Stephanie C. Stotz, et al.
Published: (2008-01-01)

Correction: Citral Sensing by Transient Receptor Potential Channels in Dorsal Root Ganglion Neurons
Published: (2008-01-01)

Nuclear Magnetic Resonance Treatment Accelerates the Regeneration of Dorsal Root Ganglion Neurons in vitro
by: Anda Mann, et al.
Published: (2022-03-01)

A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction
by: Benjamin M. Zemel, et al.
Published: (2018-08-01)

Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice
by: Haohao Wu, et al.
Published: (2021-02-01)

Adrenergic receptors inhibit TRPV1 activity in the dorsal root ganglion neurons of rats.
by: Yumi Matsushita, et al.
Published: (2018-01-01)