Randomized controlled trial protocol to investigate the antiplatelet therapy effect on extracellular vesicles (AFFECT EV) in acute myocardial infarction

Randomized controlled trial protocol to investigate the antiplatelet therapy effect on extracellular vesicles (AFFECT EV) in acute myocardial infarction

Activated platelets contribute to thrombosis and inflammation by the release of extracellular vesicles (EVs) exposing P-selectin, phosphatidylserine (PS) and fibrinogen. P2Y12 receptor antagonists are routinely administered to inhibit platelet activation in patients after acute myocardial infarction...

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Bibliographic Details
Main Authors: Aleksandra Gasecka, Rienk Nieuwland, Monika Budnik, Françoise Dignat-George, Ceren Eyileten, Paul Harrison, Zenon Huczek, Agnieszka Kapłon-Cieślicka, Romaric Lacroix, Grzegorz Opolski, Kinga Pluta, Edwin van der Pol, Marek Postuła, Aurélie Leroyer, Pia Siljander, Auguste Sturk, Krzysztof J. Filipiak
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Platelets
Subjects:
adp receptors
extracellular vesicles
p2y12 antagonists
platelets
ticagrelor
Online Access:http://dx.doi.org/10.1080/09537104.2018.1557616

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