Inhibition of Tongue Coat and Dental Plaque Formation by Stabilized Chlorine Dioxide Vs Chlorhexidine Mouthrinse: A Randomized, Triple Blinded Study
Background: Chlorine dioxide (ClO2 ) is an oxidizing agent with known bactericidal, viricidal and fungicidal properties. Its efficacy in reducing the halitosis has been established by previous literature. However, data evaluating its antiplaque property is scarce. Chlorhexidine (CHX) is conside...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2015-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/6510/14587_CE[Ra1]_F(AK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf |
| _version_ | 1818067489159905280 |
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| author | Seema Roodmal Yadav Vineet Vaman Kini Ashvini Padhye |
| author_facet | Seema Roodmal Yadav Vineet Vaman Kini Ashvini Padhye |
| author_sort | Seema Roodmal Yadav |
| collection | DOAJ |
| description | Background: Chlorine dioxide (ClO2
) is an oxidizing agent
with known bactericidal, viricidal and fungicidal properties.
Its efficacy in reducing the halitosis has been established by
previous literature. However, data evaluating its antiplaque
property is scarce. Chlorhexidine (CHX) is considered as the
gold standard and an effective adjunctive to mechanical
plaque removal. However, it is associated with few reversible
side effects. Therefore a study was conducted to assess the
antiplaque property of ClO2
containing mouthrinse against CHX
mouthrinse.
Aims and Objectives: To evaluate the efficacy of stabilized
chlorine dioxide containing mouthrinse and CHX containing
mouthrinse in inhibition of tongue coat accumulation and dental
plaque formation using a four day plaque regrowth model
clinically and microbiologically in a healthy dental cohort.
Materials and Methods: A Single Center, Randomized, Triple
blinded, Microbiological clinical trial was conducted involving 25
healthy dental students volunteers (11 males, 14 females). Two
commercially available mouthrinse: Mouthrinse A – Aqueous
based ClO2
mouthrinse Freshchlor® and Mouthrinse B - Aqueous
based 0.2% CHX mouthrinse Hexidine® were selected as the
test products. Subjects were asked to rinse and gargle for 1
minute with the allocated mouthrinse under supervision after
supragingival scaling, polishing and tongue coat removal.
After four hours, smears were taken from the buccal mucosa
and tooth surface. On the fifth day from baseline of four day non
brushing plaque regrowth model the samples were again taken
from buccal mucosa and tooth surface followed by recording of
plaque scores by Rastogi Modification of Navy Plaque index,
extent of tongue coat by Winkel’s tongue coating index and
measuring tongue coat wet weight in grams. The samples
collected were subjected to microbial analysis and the results
were expressed as colony forming units (CFUs) per sample.
Statistical Analysis: The Data was analysed using SPSS 16.00
and presented using descriptive statistics. Independent t-test
was used for the comparison between mouthrinse A groups &
mouthrinse B group.
Results: The plaque scores and Winkels tongue coat scores,
wet tongue coat weight recorded on the fifth day after the use
of the two mouthrinse didn’t show a statistically significant
difference. The CFU per sample from tooth and mucosa
after four hours revealed low bacteria count with respect to
mouthrinse B however the CFU obtained on the fifth day did
not show a statistically significant difference between the two
mouthrinse.
Conclusion: The clinical antiplaque efficacy of CHX and ClO2
mouthwash is comparable and so is the efficacy in reducing the
oral bacterial load. |
| first_indexed | 2024-12-10T15:24:29Z |
| format | Article |
| id | doaj.art-2be1b53e3abf431f891d8a8d1f4c1302 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-10T15:24:29Z |
| publishDate | 2015-09-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-2be1b53e3abf431f891d8a8d1f4c13022022-12-22T01:43:34ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-09-0199ZC69ZC7410.7860/JCDR/2015/14587.6510Inhibition of Tongue Coat and Dental Plaque Formation by Stabilized Chlorine Dioxide Vs Chlorhexidine Mouthrinse: A Randomized, Triple Blinded StudySeema Roodmal Yadav0Vineet Vaman Kini1Ashvini Padhye2Post Graduate Student, Department of Periodontology, Mahatma Gandhi Mission’s Dental College and Hospital, Kamothe, Navi Mumbai, Maharashtra, India.Professor, Department of Periodontology, Mahatma Gandhi Mission’s Dental College and Hospital, Kamothe, Navi Mumbai, Maharashtra, India.Professor and Head of Department, Department of Periodontology, Mahatma Gandhi Mission’s Dental College and Hospital, Kamothe, Navi Mumbai, Maharashtra, India.Background: Chlorine dioxide (ClO2 ) is an oxidizing agent with known bactericidal, viricidal and fungicidal properties. Its efficacy in reducing the halitosis has been established by previous literature. However, data evaluating its antiplaque property is scarce. Chlorhexidine (CHX) is considered as the gold standard and an effective adjunctive to mechanical plaque removal. However, it is associated with few reversible side effects. Therefore a study was conducted to assess the antiplaque property of ClO2 containing mouthrinse against CHX mouthrinse. Aims and Objectives: To evaluate the efficacy of stabilized chlorine dioxide containing mouthrinse and CHX containing mouthrinse in inhibition of tongue coat accumulation and dental plaque formation using a four day plaque regrowth model clinically and microbiologically in a healthy dental cohort. Materials and Methods: A Single Center, Randomized, Triple blinded, Microbiological clinical trial was conducted involving 25 healthy dental students volunteers (11 males, 14 females). Two commercially available mouthrinse: Mouthrinse A – Aqueous based ClO2 mouthrinse Freshchlor® and Mouthrinse B - Aqueous based 0.2% CHX mouthrinse Hexidine® were selected as the test products. Subjects were asked to rinse and gargle for 1 minute with the allocated mouthrinse under supervision after supragingival scaling, polishing and tongue coat removal. After four hours, smears were taken from the buccal mucosa and tooth surface. On the fifth day from baseline of four day non brushing plaque regrowth model the samples were again taken from buccal mucosa and tooth surface followed by recording of plaque scores by Rastogi Modification of Navy Plaque index, extent of tongue coat by Winkel’s tongue coating index and measuring tongue coat wet weight in grams. The samples collected were subjected to microbial analysis and the results were expressed as colony forming units (CFUs) per sample. Statistical Analysis: The Data was analysed using SPSS 16.00 and presented using descriptive statistics. Independent t-test was used for the comparison between mouthrinse A groups & mouthrinse B group. Results: The plaque scores and Winkels tongue coat scores, wet tongue coat weight recorded on the fifth day after the use of the two mouthrinse didn’t show a statistically significant difference. The CFU per sample from tooth and mucosa after four hours revealed low bacteria count with respect to mouthrinse B however the CFU obtained on the fifth day did not show a statistically significant difference between the two mouthrinse. Conclusion: The clinical antiplaque efficacy of CHX and ClO2 mouthwash is comparable and so is the efficacy in reducing the oral bacterial load.https://jcdr.net/articles/PDF/6510/14587_CE[Ra1]_F(AK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdfbacterial countmicrobial activityperiodontal disease |
| spellingShingle | Seema Roodmal Yadav Vineet Vaman Kini Ashvini Padhye Inhibition of Tongue Coat and Dental Plaque Formation by Stabilized Chlorine Dioxide Vs Chlorhexidine Mouthrinse: A Randomized, Triple Blinded Study Journal of Clinical and Diagnostic Research bacterial count microbial activity periodontal disease |
| title | Inhibition of Tongue Coat and Dental Plaque Formation by Stabilized Chlorine Dioxide Vs Chlorhexidine Mouthrinse: A Randomized, Triple Blinded Study |
| title_full | Inhibition of Tongue Coat and Dental Plaque Formation by Stabilized Chlorine Dioxide Vs Chlorhexidine Mouthrinse: A Randomized, Triple Blinded Study |
| title_fullStr | Inhibition of Tongue Coat and Dental Plaque Formation by Stabilized Chlorine Dioxide Vs Chlorhexidine Mouthrinse: A Randomized, Triple Blinded Study |
| title_full_unstemmed | Inhibition of Tongue Coat and Dental Plaque Formation by Stabilized Chlorine Dioxide Vs Chlorhexidine Mouthrinse: A Randomized, Triple Blinded Study |
| title_short | Inhibition of Tongue Coat and Dental Plaque Formation by Stabilized Chlorine Dioxide Vs Chlorhexidine Mouthrinse: A Randomized, Triple Blinded Study |
| title_sort | inhibition of tongue coat and dental plaque formation by stabilized chlorine dioxide vs chlorhexidine mouthrinse a randomized triple blinded study |
| topic | bacterial count microbial activity periodontal disease |
| url | https://jcdr.net/articles/PDF/6510/14587_CE[Ra1]_F(AK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf |
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