Identification of spermatogenesis-associated changes in DNA methylation induced by maternal exposure to chemicals in male germ cells

Summary: It is now recognized that maternal environmental factors, including chemical exposure and nutritional conditions, alter DNA methylation patterns in fetal germ cells, subsequently affecting germ cell development as well as offspring phenotypes. Here, we describe steps for detecting DNA methy...

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Bibliographic Details
Main Authors: Yukiko Tando, Yasuhisa Matsui
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722007924