Association of Cerebral Ischemia With Corneal Nerve Loss and Brain Atrophy in MCI and Dementia

Association of Cerebral Ischemia With Corneal Nerve Loss and Brain Atrophy in MCI and Dementia

IntroductionThis study assessed the association of cerebral ischemia with neurodegeneration in mild cognitive impairment (MCI) and dementia.MethodsSubjects with MCI, dementia and controls underwent assessment of cognitive function, severity of brain ischemia, MRI brain volumetry and corneal confocal...

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Main Authors: Georgios Ponirakis, Ahmed Elsotouhy, Hanadi Al Hamad, Surjith Vattoth, Ioannis N. Petropoulos, Adnan Khan, Hoda Gad, Fatima Al-Khayat, Mani Chandran, Marwan Ramadan, Marwa Elorrabi, Masharig Gadelseed, Rhia Tosino, Priya V. Gawhale, Maryam Alobaidi, Shafi Khan, Pravija Manikoth, Yasmin H. M. Abdelrahim, Noushad Thodi, Hamad Almuhannadi, Salma Al-Mohannadi, Fatema AlMarri, Murtaza Qazi, Ahmed Own, Ziyad R. Mahfoud, Ashfaq Shuaib, Rayaz A. Malik
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Neuroscience
Subjects:
ischemic lesions
surrogate marker
corneal confocal microscopy
corneal nerve fibers
brain atrophy
dementia
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.690896/full

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