High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar
Abstract Background A school-based survey was undertaken to assess prevalence and infection intensity of schistosomiasis in school-aged children in the Marolambo District of Madagascar. Methods School-aged children from six purposively selected schools were tested for Schistosoma haematobium by urin...
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| Format: | Article |
| Language: | English |
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BMC
2017-06-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13071-017-2249-7 |
| _version_ | 1811301860888281088 |
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| author | Stephen A. Spencer James M. St. John Penney Hannah J. Russell Anthony P. Howe Cortland Linder Andriamahitsisambatra L. D. Rakotomampianina Anjara M. Nandimbiniaina S Bertel Squire J. Russell Stothard Amaya L. Bustinduy Alain M. Rahetilahy |
| author_facet | Stephen A. Spencer James M. St. John Penney Hannah J. Russell Anthony P. Howe Cortland Linder Andriamahitsisambatra L. D. Rakotomampianina Anjara M. Nandimbiniaina S Bertel Squire J. Russell Stothard Amaya L. Bustinduy Alain M. Rahetilahy |
| author_sort | Stephen A. Spencer |
| collection | DOAJ |
| description | Abstract Background A school-based survey was undertaken to assess prevalence and infection intensity of schistosomiasis in school-aged children in the Marolambo District of Madagascar. Methods School-aged children from six purposively selected schools were tested for Schistosoma haematobium by urine filtration and Schistosoma mansoni using circulating cathodic antigen (CCA) and Kato-Katz stool analysis. The investigators did not address soil-transmitted helminths (STH) in this study. Results Of 399 school-aged children screened, 93.7% were infected with S. mansoni based on CCA analysis. Kato-Katz analysis of stool revealed S. mansoni infection in 73.6% (215/ 292). Heavy infections (> 400 eggs per gram) were common (32.1%; 69/ 215), with a mean of 482 eggs per gram of stool. Moderate infection intensities were detected in 31.2% (67/ 215) and light infection intensities in 36.7% (79/ 215) of infected participants. No infection with S. haematobium was detected by urine filtration. Conclusions Intestinal schistosomiasis appears a considerable public health issue in this remote area of Madagascar where there is a pressing need for mass drug administration. |
| first_indexed | 2024-04-13T07:17:44Z |
| format | Article |
| id | doaj.art-2be2b2a2841b4a15970a38e856d2dab9 |
| institution | Directory Open Access Journal |
| issn | 1756-3305 |
| language | English |
| last_indexed | 2024-04-13T07:17:44Z |
| publishDate | 2017-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Parasites & Vectors |
| spelling | doaj.art-2be2b2a2841b4a15970a38e856d2dab92022-12-22T02:56:42ZengBMCParasites & Vectors1756-33052017-06-011011810.1186/s13071-017-2249-7High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, MadagascarStephen A. Spencer0James M. St. John Penney1Hannah J. Russell2Anthony P. Howe3Cortland Linder4Andriamahitsisambatra L. D. Rakotomampianina5Anjara M. Nandimbiniaina6S Bertel Squire7J. Russell Stothard8Amaya L. Bustinduy9Alain M. Rahetilahy10Royal United Hospitals Bath NHS Foundation TrustThe University of Manchester Medical SchoolThe University of Manchester Medical SchoolThe University of Manchester Medical SchoolThe University of Manchester Medical SchoolUniversité d’AntananarivoUniversité d’AntananarivoLiverpool School of Tropical MedicineLiverpool School of Tropical MedicineLondon School of Hygiene & Tropical MedicineMinistère de la Santé PubliqueAbstract Background A school-based survey was undertaken to assess prevalence and infection intensity of schistosomiasis in school-aged children in the Marolambo District of Madagascar. Methods School-aged children from six purposively selected schools were tested for Schistosoma haematobium by urine filtration and Schistosoma mansoni using circulating cathodic antigen (CCA) and Kato-Katz stool analysis. The investigators did not address soil-transmitted helminths (STH) in this study. Results Of 399 school-aged children screened, 93.7% were infected with S. mansoni based on CCA analysis. Kato-Katz analysis of stool revealed S. mansoni infection in 73.6% (215/ 292). Heavy infections (> 400 eggs per gram) were common (32.1%; 69/ 215), with a mean of 482 eggs per gram of stool. Moderate infection intensities were detected in 31.2% (67/ 215) and light infection intensities in 36.7% (79/ 215) of infected participants. No infection with S. haematobium was detected by urine filtration. Conclusions Intestinal schistosomiasis appears a considerable public health issue in this remote area of Madagascar where there is a pressing need for mass drug administration.http://link.springer.com/article/10.1186/s13071-017-2249-7SchistosomiasisSchistosoma mansoniNeglected diseasesChild healthRural healthMadagascar |
| spellingShingle | Stephen A. Spencer James M. St. John Penney Hannah J. Russell Anthony P. Howe Cortland Linder Andriamahitsisambatra L. D. Rakotomampianina Anjara M. Nandimbiniaina S Bertel Squire J. Russell Stothard Amaya L. Bustinduy Alain M. Rahetilahy High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar Parasites & Vectors Schistosomiasis Schistosoma mansoni Neglected diseases Child health Rural health Madagascar |
| title | High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar |
| title_full | High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar |
| title_fullStr | High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar |
| title_full_unstemmed | High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar |
| title_short | High burden of Schistosoma mansoni infection in school-aged children in Marolambo District, Madagascar |
| title_sort | high burden of schistosoma mansoni infection in school aged children in marolambo district madagascar |
| topic | Schistosomiasis Schistosoma mansoni Neglected diseases Child health Rural health Madagascar |
| url | http://link.springer.com/article/10.1186/s13071-017-2249-7 |
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