The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy
Xerostomia is a common complication post-radiotherapy in patients with oral cancer. The acute and long-term side effects can considerably reduce the patient’s quality of life. The aim of our study was to perform analysis of salivary flow and pH in patients after radiotherapy. Methodology: Clinical a...
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| Format: | Article |
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MDPI AG
2022-04-01
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| Online Access: | https://www.mdpi.com/2076-3417/12/8/3708 |
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| author | Bogdan Petru Bulancea Laura Elisabeta Checherita Georgeta Liliana Foia Ovidiu Stamatin Silvia Teslaru Iulian Costin Lupu Delia Gabriela Ciobanu Eduard-Radu Cernei Grierosu Carmen Mariana Postolache Eliza Maria Froicu Liliana Gabriela Halitchi Liana Aminov |
| author_facet | Bogdan Petru Bulancea Laura Elisabeta Checherita Georgeta Liliana Foia Ovidiu Stamatin Silvia Teslaru Iulian Costin Lupu Delia Gabriela Ciobanu Eduard-Radu Cernei Grierosu Carmen Mariana Postolache Eliza Maria Froicu Liliana Gabriela Halitchi Liana Aminov |
| author_sort | Bogdan Petru Bulancea |
| collection | DOAJ |
| description | Xerostomia is a common complication post-radiotherapy in patients with oral cancer. The acute and long-term side effects can considerably reduce the patient’s quality of life. The aim of our study was to perform analysis of salivary flow and pH in patients after radiotherapy. Methodology: Clinical and laboratory evaluations were conducted in the 2014–2019 period; out of a total 58 subjects aged between 45 and 84, 28 individuals with oral cancer were selected from St. Spiridon Hospital, Clinic of Maxillo-facial Surgery and Oncology Hospital, Iasi post-radiotherapy. Results: Significant downsized mean values of the hydrogen ion concentration (pH) in saliva (<i>p</i> < 0.001) were recorded in patients after radiotherapy, pH value = 4.580 (±1.051). The mean value of resting salivary flow (MRSF) was significantly lower for the group of patients with radiotherapy (MRSF) = 0.145 mL/min. In 89.29% of cases (25 post-radiotherapy cases), in order to perform oral complex rehabilitation treatment, several endodontic and periodontal treatments were performed. A total of 78.57% of the cases received complex oral rehabilitation as mobile or hybrid prostheses or fixed solutions. Conclusion: Understanding post-radiotherapy salivary biochemic modifications in patients with oral cancer could be of critical importance, in view of related oral disorder prevention. |
| first_indexed | 2024-03-09T11:13:45Z |
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| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T11:13:45Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-2be47e95fbb84633b86b6f00a00c41632023-12-01T00:37:08ZengMDPI AGApplied Sciences2076-34172022-04-01128370810.3390/app12083708The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-RadiotherapyBogdan Petru Bulancea0Laura Elisabeta Checherita1Georgeta Liliana Foia2Ovidiu Stamatin3Silvia Teslaru4Iulian Costin Lupu5Delia Gabriela Ciobanu6Eduard-Radu Cernei7Grierosu Carmen8Mariana Postolache9Eliza Maria Froicu10Liliana Gabriela Halitchi11Liana Aminov123rd Department of Oral Implantology, Removable Dentures and Dental Prostheses Technology, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, Romania2nd Department of Odontology, Periodontology and Fixed Prosthesis, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, RomaniaDepartment of Dental Alveolar and Maxillar-Facial Surgery, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, Romania3rd Department of Oral Implantology, Removable Dentures and Dental Prostheses Technology, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, Romania2nd Department of Odontology, Periodontology and Fixed Prosthesis, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, Romania3rd Department of Oral Implantology, Removable Dentures and Dental Prostheses Technology, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, Romania1st Department of Morpho-Functional Sciences, Faculty of General Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, RomaniaDepartment of Dental Alveolar and Maxillar-Facial Surgery, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, RomaniaFaculty of Dentistry, Apollonia Iasi University, Pacurari 11 Streets, 700511 Iasi, RomaniaMinistry of Health, Programme Implementation Unit, 1-3 Cristian Popisteanu Street, 010024 Bucharest, RomaniaFaculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, RomaniaDepartment of Dental Alveolar and Maxillar-Facial Surgery, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, Romania2nd Department of Odontology, Periodontology and Fixed Prosthesis, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 Universității Street, 700115 Iasi, RomaniaXerostomia is a common complication post-radiotherapy in patients with oral cancer. The acute and long-term side effects can considerably reduce the patient’s quality of life. The aim of our study was to perform analysis of salivary flow and pH in patients after radiotherapy. Methodology: Clinical and laboratory evaluations were conducted in the 2014–2019 period; out of a total 58 subjects aged between 45 and 84, 28 individuals with oral cancer were selected from St. Spiridon Hospital, Clinic of Maxillo-facial Surgery and Oncology Hospital, Iasi post-radiotherapy. Results: Significant downsized mean values of the hydrogen ion concentration (pH) in saliva (<i>p</i> < 0.001) were recorded in patients after radiotherapy, pH value = 4.580 (±1.051). The mean value of resting salivary flow (MRSF) was significantly lower for the group of patients with radiotherapy (MRSF) = 0.145 mL/min. In 89.29% of cases (25 post-radiotherapy cases), in order to perform oral complex rehabilitation treatment, several endodontic and periodontal treatments were performed. A total of 78.57% of the cases received complex oral rehabilitation as mobile or hybrid prostheses or fixed solutions. Conclusion: Understanding post-radiotherapy salivary biochemic modifications in patients with oral cancer could be of critical importance, in view of related oral disorder prevention.https://www.mdpi.com/2076-3417/12/8/3708oral cancerpost-radiotherapy (RT)salivary pHsalivary flow rate (SFR)intraoral complex rehabilitation treatmentstomatognatic system (SS) |
| spellingShingle | Bogdan Petru Bulancea Laura Elisabeta Checherita Georgeta Liliana Foia Ovidiu Stamatin Silvia Teslaru Iulian Costin Lupu Delia Gabriela Ciobanu Eduard-Radu Cernei Grierosu Carmen Mariana Postolache Eliza Maria Froicu Liliana Gabriela Halitchi Liana Aminov The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy Applied Sciences oral cancer post-radiotherapy (RT) salivary pH salivary flow rate (SFR) intraoral complex rehabilitation treatment stomatognatic system (SS) |
| title | The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy |
| title_full | The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy |
| title_fullStr | The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy |
| title_full_unstemmed | The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy |
| title_short | The Quantification of Salivary Flow and pH and Stomatognathic System Rehabilitation Interference in Patients with Oral Diseases, Post-Radiotherapy |
| title_sort | quantification of salivary flow and ph and stomatognathic system rehabilitation interference in patients with oral diseases post radiotherapy |
| topic | oral cancer post-radiotherapy (RT) salivary pH salivary flow rate (SFR) intraoral complex rehabilitation treatment stomatognatic system (SS) |
| url | https://www.mdpi.com/2076-3417/12/8/3708 |
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