The change of anterior segment parameters after cataract surgery in normal-tension glaucoma
AIM: To investigate the change of anterior chamber angle morphology and intraocular pressure (IOP) reduction after cataract surgery in patients with normal-tension glaucoma (NTG) using swept-source optical coherence tomography (SS-OCT). METHODS: This prospective, comparative, observational study re...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2017-08-01
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| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.cn/en_publish/2017/8/20170809.pdf |
| _version_ | 1818034955955994624 |
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| author | Wonseok Lee Hyoung Won Bae Chan Yun Kim Gong Je Seong |
| author_facet | Wonseok Lee Hyoung Won Bae Chan Yun Kim Gong Je Seong |
| author_sort | Wonseok Lee |
| collection | DOAJ |
| description | AIM: To investigate the change of anterior chamber angle morphology and intraocular pressure (IOP) reduction after cataract surgery in patients with normal-tension glaucoma (NTG) using swept-source optical coherence tomography (SS-OCT).
METHODS: This prospective, comparative, observational study recruited patients into two groups. Group 1 was the control group including normal subjects except those with cataracts (cataract group, n=67 eyes of 67 patients), and group 2 was NTG group including patients who were diagnosed with NTG and cataracts (n=43 eyes of 43 patients), which were treated with phacoemulsification and intraocular lens implantation. Before surgery, and at postoperative 1 and 6mo, anterior chamber angles were evaluated by SS-OCT under dark conditions using three-dimensional angle analysis scan protocol. Angle opening distance (AOD), angle recess area (ARA), and trabecular-iris surface area (TISA) at four quadrants (temporal, nasal, superior, and inferior) were calculated automatically by SS-OCT, after the observer marked scleral spurs.
RESULTS: A total of 106 patients (54 males and 52 females) were enrolled in the study. Angle parameters, AOD, ARA, and TISA were increased after surgery in both groups. However, changes of angle parameters were only significant in group 2. In group 2, preoperative IOP was 13.2±2.9 mm Hg, and postoperative IOP at 1 and 6mo were 10.5±3.0 and 10.7±2.8 mm Hg, respectively. In group 1, preoperative IOP was 12.4±2.8 mm Hg, and postoperative IOP at 1 and 6mo were 11.6±2.5 and 12.0±2.8 mm Hg, respectively. After cataract surgery, angle parameters changed significantly while IOP significantly reduced and was maintained in group 2 (P<0.001). The changes in angle parameters (ΔAOD500, ΔTISA500 at temporal; ΔAOD500, ΔARA500 at nasal) were linearly correlated with postoperative IOP changes.
CONCLUSION: Cataract surgery may have improved anterior chamber angle parameters and decreased IOP in NTG patients. |
| first_indexed | 2024-12-10T06:47:23Z |
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| id | doaj.art-2be74943034f4a87b5b077b5fb50fa05 |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-12-10T06:47:23Z |
| publishDate | 2017-08-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
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| series | International Journal of Ophthalmology |
| spelling | doaj.art-2be74943034f4a87b5b077b5fb50fa052022-12-22T01:58:38ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982017-08-011081239124510.18240/ijo.2017.08.09The change of anterior segment parameters after cataract surgery in normal-tension glaucomaWonseok Lee0Hyoung Won Bae1Chan Yun Kim2Gong Je Seong3Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, KoreaInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, KoreaInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, KoreaInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul 03722, KoreaAIM: To investigate the change of anterior chamber angle morphology and intraocular pressure (IOP) reduction after cataract surgery in patients with normal-tension glaucoma (NTG) using swept-source optical coherence tomography (SS-OCT). METHODS: This prospective, comparative, observational study recruited patients into two groups. Group 1 was the control group including normal subjects except those with cataracts (cataract group, n=67 eyes of 67 patients), and group 2 was NTG group including patients who were diagnosed with NTG and cataracts (n=43 eyes of 43 patients), which were treated with phacoemulsification and intraocular lens implantation. Before surgery, and at postoperative 1 and 6mo, anterior chamber angles were evaluated by SS-OCT under dark conditions using three-dimensional angle analysis scan protocol. Angle opening distance (AOD), angle recess area (ARA), and trabecular-iris surface area (TISA) at four quadrants (temporal, nasal, superior, and inferior) were calculated automatically by SS-OCT, after the observer marked scleral spurs. RESULTS: A total of 106 patients (54 males and 52 females) were enrolled in the study. Angle parameters, AOD, ARA, and TISA were increased after surgery in both groups. However, changes of angle parameters were only significant in group 2. In group 2, preoperative IOP was 13.2±2.9 mm Hg, and postoperative IOP at 1 and 6mo were 10.5±3.0 and 10.7±2.8 mm Hg, respectively. In group 1, preoperative IOP was 12.4±2.8 mm Hg, and postoperative IOP at 1 and 6mo were 11.6±2.5 and 12.0±2.8 mm Hg, respectively. After cataract surgery, angle parameters changed significantly while IOP significantly reduced and was maintained in group 2 (P<0.001). The changes in angle parameters (ΔAOD500, ΔTISA500 at temporal; ΔAOD500, ΔARA500 at nasal) were linearly correlated with postoperative IOP changes. CONCLUSION: Cataract surgery may have improved anterior chamber angle parameters and decreased IOP in NTG patients.http://www.ijo.cn/en_publish/2017/8/20170809.pdf1245normal-tension glaucomacataract surgeryintraocular pressure reductionswept-source optical coherence tomographyangle parameters |
| spellingShingle | Wonseok Lee Hyoung Won Bae Chan Yun Kim Gong Je Seong The change of anterior segment parameters after cataract surgery in normal-tension glaucoma International Journal of Ophthalmology 1245 normal-tension glaucoma cataract surgery intraocular pressure reduction swept-source optical coherence tomography angle parameters |
| title | The change of anterior segment parameters after cataract surgery in normal-tension glaucoma |
| title_full | The change of anterior segment parameters after cataract surgery in normal-tension glaucoma |
| title_fullStr | The change of anterior segment parameters after cataract surgery in normal-tension glaucoma |
| title_full_unstemmed | The change of anterior segment parameters after cataract surgery in normal-tension glaucoma |
| title_short | The change of anterior segment parameters after cataract surgery in normal-tension glaucoma |
| title_sort | change of anterior segment parameters after cataract surgery in normal tension glaucoma |
| topic | 1245 normal-tension glaucoma cataract surgery intraocular pressure reduction swept-source optical coherence tomography angle parameters |
| url | http://www.ijo.cn/en_publish/2017/8/20170809.pdf |
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