Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages

Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages

Human norovirus (HNV) is one of the emerging and rapidly spreading groups of pathogens and the main cause of epidemic viral gastroenteritis globally. Due to a lack of in vitro culture systems and suitable animal models for HNV infection, murine norovirus (MNV) has become a common model. A recent stu...

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Bibliographic Details
Main Authors: Ming Fu, Nini Chen, Yanhe Zhou, Sidong Chen, Wanfu Xu, Sitang Gong, Lanlan Geng
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Vaccines
Subjects:
MNV
jatrorrhizine
NLRP3
inflammasome
pyroptosis
Online Access:https://www.mdpi.com/2076-393X/11/1/164

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