Type 2 Diabetes Prescribing Habits Amongst Providers to an Underserved Population

Introduction: Type 2 diabetes mellitus (T2DM) affected over 30 million individuals in the United States as of 2015. Due to the national diabetes guidelines recommending drug selection based on several patient specific factors and varying formulary restrictions, prescribers are often inundated when s...

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Main Authors: Cynthia King, Atem Fontem, Benjamin King, Dave Gothard
Format: Article
Language:English
Published: University of Minnesota Libraries Publishing 2019-11-01
Series:INNOVATIONS in Pharmacy
Subjects:
Online Access:https://pubs.lib.umn.edu/index.php/innovations/article/view/2151
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author Cynthia King
Atem Fontem
Benjamin King
Dave Gothard
author_facet Cynthia King
Atem Fontem
Benjamin King
Dave Gothard
author_sort Cynthia King
collection DOAJ
description Introduction: Type 2 diabetes mellitus (T2DM) affected over 30 million individuals in the United States as of 2015. Due to the national diabetes guidelines recommending drug selection based on several patient specific factors and varying formulary restrictions, prescribers are often inundated when selecting treatment. Currently, limited evidence is available regarding the primary factors influencing prescribers’ drug therapy selection. Objectives: The purpose of this study was to identify factors that influence providers during T2DM medication selection. Methods: The study was conducted with providers at a large, academic, safety net health system. All prescribers were sent an electronic, optional and anonymous survey. Prescribers treating T2DM in non-pregnant adult patients were the only prescribers assessed. Factors evaluated were: cost, A1c, comorbidities, adherence, weight, tolerability, patient limitations, and use of guidelines. Results: A total of 86 prescribers responded, yielding a response rate of 31%. The respondents included physicians (56.3%), nurse practitioners (21.8%), medical residents (18.4%), and fellows (3.4%); with the majority practicing in internal or family medicine (47.1%). The most frequently prescribed T2DM medications included: metformin (83.8%), insulin (78.1%), and sulfonylureas (64.8%). Cost and A1c elevation were two of the major factors influencing prescribing of metformin (94.1% and 81.2%), insulin (57.4% and 69.6%), and sulfonylureas (81.2% and 89.9%) respectively. Due to cost concerns, respondents reported rarely or never prescribing glucagon-like peptide-1 agonists (GLP-1RA) and sodium-glucose co-transporter-2 inhibitors (SGLT2i) despite recognizing benefits on diabetes related comorbidities.   Conclusion: Although current literature from the national guidelines encourages the use of GLP-1RA and SGLT2i as first-line options after metformin in T2DM, these classes of medications were not reported among the most commonly prescribed despite providers correctly identifying positive medication attributes such as cardio- and nephroprotection and weight loss. However, cost of these medications appears to outweigh the benefits when selecting medication therapy.   Article Type: Original Research
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spelling doaj.art-2bece36fa42a41cbbf8a389f8543c73f2022-12-22T02:59:28ZengUniversity of Minnesota Libraries PublishingINNOVATIONS in Pharmacy2155-04172019-11-0110410.24926/iip.v10i4.2151Type 2 Diabetes Prescribing Habits Amongst Providers to an Underserved PopulationCynthia King0Atem Fontem1Benjamin King2Dave Gothard3MetroHealth SystemMetroHealth SystemMetroHealth SystemData Analysis for Clinical Research StudiesIntroduction: Type 2 diabetes mellitus (T2DM) affected over 30 million individuals in the United States as of 2015. Due to the national diabetes guidelines recommending drug selection based on several patient specific factors and varying formulary restrictions, prescribers are often inundated when selecting treatment. Currently, limited evidence is available regarding the primary factors influencing prescribers’ drug therapy selection. Objectives: The purpose of this study was to identify factors that influence providers during T2DM medication selection. Methods: The study was conducted with providers at a large, academic, safety net health system. All prescribers were sent an electronic, optional and anonymous survey. Prescribers treating T2DM in non-pregnant adult patients were the only prescribers assessed. Factors evaluated were: cost, A1c, comorbidities, adherence, weight, tolerability, patient limitations, and use of guidelines. Results: A total of 86 prescribers responded, yielding a response rate of 31%. The respondents included physicians (56.3%), nurse practitioners (21.8%), medical residents (18.4%), and fellows (3.4%); with the majority practicing in internal or family medicine (47.1%). The most frequently prescribed T2DM medications included: metformin (83.8%), insulin (78.1%), and sulfonylureas (64.8%). Cost and A1c elevation were two of the major factors influencing prescribing of metformin (94.1% and 81.2%), insulin (57.4% and 69.6%), and sulfonylureas (81.2% and 89.9%) respectively. Due to cost concerns, respondents reported rarely or never prescribing glucagon-like peptide-1 agonists (GLP-1RA) and sodium-glucose co-transporter-2 inhibitors (SGLT2i) despite recognizing benefits on diabetes related comorbidities.   Conclusion: Although current literature from the national guidelines encourages the use of GLP-1RA and SGLT2i as first-line options after metformin in T2DM, these classes of medications were not reported among the most commonly prescribed despite providers correctly identifying positive medication attributes such as cardio- and nephroprotection and weight loss. However, cost of these medications appears to outweigh the benefits when selecting medication therapy.   Article Type: Original Researchhttps://pubs.lib.umn.edu/index.php/innovations/article/view/2151Type 2 diabetes mellitus, prescribing habits, clinical decision making, comorbidities, treatment choices
spellingShingle Cynthia King
Atem Fontem
Benjamin King
Dave Gothard
Type 2 Diabetes Prescribing Habits Amongst Providers to an Underserved Population
INNOVATIONS in Pharmacy
Type 2 diabetes mellitus, prescribing habits, clinical decision making, comorbidities, treatment choices
title Type 2 Diabetes Prescribing Habits Amongst Providers to an Underserved Population
title_full Type 2 Diabetes Prescribing Habits Amongst Providers to an Underserved Population
title_fullStr Type 2 Diabetes Prescribing Habits Amongst Providers to an Underserved Population
title_full_unstemmed Type 2 Diabetes Prescribing Habits Amongst Providers to an Underserved Population
title_short Type 2 Diabetes Prescribing Habits Amongst Providers to an Underserved Population
title_sort type 2 diabetes prescribing habits amongst providers to an underserved population
topic Type 2 diabetes mellitus, prescribing habits, clinical decision making, comorbidities, treatment choices
url https://pubs.lib.umn.edu/index.php/innovations/article/view/2151
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