Effect of immune stimulator Ismigen on immunological indicators of children with obstructive bronchitis
One of the leading positions among the infant diseases belongs to the pathology of the respiratory tract. The causes of the obstructive bronchitis in children are very diverse including those, which can be associated with the disorder of the normal immune system functioning or immunodeficiency state...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Ltd. “The National Academy of Pediatric Science and Innovation”
2018-03-01
|
| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/626 |
| _version_ | 1797875225665208320 |
|---|---|
| author | T. B. Kasokhov Z. A. Tsoraeva O. T. Bekuzarova S. V. Turieva A. I. Mazur |
| author_facet | T. B. Kasokhov Z. A. Tsoraeva O. T. Bekuzarova S. V. Turieva A. I. Mazur |
| author_sort | T. B. Kasokhov |
| collection | DOAJ |
| description | One of the leading positions among the infant diseases belongs to the pathology of the respiratory tract. The causes of the obstructive bronchitis in children are very diverse including those, which can be associated with the disorder of the normal immune system functioning or immunodeficiency state. The purpose of the study is to determine the nature of the immune disorders in the children with the obstructive bronchitis, to assess the efficiency of the immunocorrecting therapy. For 2 groups of the children with the obstructive bronchitis, the comparative study with determination of the cytokine and immunoglobulin levels in the blood serum against the background of standard therapy (1st group) and against the background with immune stimulator ismigen included into the therapy was carried out; the ismigen is a multivalent antigenic complex of the bacterial lysates. The efficiency of the immune-enhancing therapy carried out towards the immune system condition of children during the comprehensive treatment of the obstructive bronchitis was shown. The practical importance of the work is to optimize diagnosis and immunocorrection in obstructive bronchitis in children, accompanied by the disorder of the body’s immunoreactivity. |
| first_indexed | 2024-04-10T01:44:16Z |
| format | Article |
| id | doaj.art-2bf1c991f6ab4693b72f85cd722c85d5 |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:44:16Z |
| publishDate | 2018-03-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-2bf1c991f6ab4693b72f85cd722c85d52023-03-13T09:12:44ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282018-03-01631969910.21508/1027-4065-2018-63-1-96-99555Effect of immune stimulator Ismigen on immunological indicators of children with obstructive bronchitisT. B. Kasokhov0Z. A. Tsoraeva1O. T. Bekuzarova2S. V. Turieva3A. I. Mazur41ФГБОУ ВО Северо-Осетинская государственная медицинская академия, Владикавказ; 2Институт биомедицинских исследований Владикавказского научного центра РАН, Владикавказ1ФГБОУ ВО Северо-Осетинская государственная медицинская академия, Владикавказ;1ФГБОУ ВО Северо-Осетинская государственная медицинская академия, Владикавказ1ФГБОУ ВО Северо-Осетинская государственная медицинская академия, Владикавказ1ФГБОУ ВО Северо-Осетинская государственная медицинская академия, ВладикавказOne of the leading positions among the infant diseases belongs to the pathology of the respiratory tract. The causes of the obstructive bronchitis in children are very diverse including those, which can be associated with the disorder of the normal immune system functioning or immunodeficiency state. The purpose of the study is to determine the nature of the immune disorders in the children with the obstructive bronchitis, to assess the efficiency of the immunocorrecting therapy. For 2 groups of the children with the obstructive bronchitis, the comparative study with determination of the cytokine and immunoglobulin levels in the blood serum against the background of standard therapy (1st group) and against the background with immune stimulator ismigen included into the therapy was carried out; the ismigen is a multivalent antigenic complex of the bacterial lysates. The efficiency of the immune-enhancing therapy carried out towards the immune system condition of children during the comprehensive treatment of the obstructive bronchitis was shown. The practical importance of the work is to optimize diagnosis and immunocorrection in obstructive bronchitis in children, accompanied by the disorder of the body’s immunoreactivity.https://www.ped-perinatology.ru/jour/article/view/626детиобструктивный бронхитиммунотерапиялизаты бактерийцитокиныиммуноглобулины |
| spellingShingle | T. B. Kasokhov Z. A. Tsoraeva O. T. Bekuzarova S. V. Turieva A. I. Mazur Effect of immune stimulator Ismigen on immunological indicators of children with obstructive bronchitis Rossijskij Vestnik Perinatologii i Pediatrii дети обструктивный бронхит иммунотерапия лизаты бактерий цитокины иммуноглобулины |
| title | Effect of immune stimulator Ismigen on immunological indicators of children with obstructive bronchitis |
| title_full | Effect of immune stimulator Ismigen on immunological indicators of children with obstructive bronchitis |
| title_fullStr | Effect of immune stimulator Ismigen on immunological indicators of children with obstructive bronchitis |
| title_full_unstemmed | Effect of immune stimulator Ismigen on immunological indicators of children with obstructive bronchitis |
| title_short | Effect of immune stimulator Ismigen on immunological indicators of children with obstructive bronchitis |
| title_sort | effect of immune stimulator ismigen on immunological indicators of children with obstructive bronchitis |
| topic | дети обструктивный бронхит иммунотерапия лизаты бактерий цитокины иммуноглобулины |
| url | https://www.ped-perinatology.ru/jour/article/view/626 |
| work_keys_str_mv | AT tbkasokhov effectofimmunestimulatorismigenonimmunologicalindicatorsofchildrenwithobstructivebronchitis AT zatsoraeva effectofimmunestimulatorismigenonimmunologicalindicatorsofchildrenwithobstructivebronchitis AT otbekuzarova effectofimmunestimulatorismigenonimmunologicalindicatorsofchildrenwithobstructivebronchitis AT svturieva effectofimmunestimulatorismigenonimmunologicalindicatorsofchildrenwithobstructivebronchitis AT aimazur effectofimmunestimulatorismigenonimmunologicalindicatorsofchildrenwithobstructivebronchitis |