Clinical application of platelet-rich fibrin to enhance dental implant stability: A systematic review and meta-analysis
Objective: To investigate the effect of platelet-rich fibrin application on implant stability. Study design: Five databases, namely, PubMed, Embase, Web of Science, Wiley, and China National Knowledge Infrastructure, were searched for reports published up to November 20, 2022. Randomized controlled...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-02-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023004036 |
| _version_ | 1811161819332476928 |
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| author | Shuai Guan Tiepeng Xiao Jiuping Bai Chunliu Ning Xingkui Zhang Lei Yang Xiangjun Li |
| author_facet | Shuai Guan Tiepeng Xiao Jiuping Bai Chunliu Ning Xingkui Zhang Lei Yang Xiangjun Li |
| author_sort | Shuai Guan |
| collection | DOAJ |
| description | Objective: To investigate the effect of platelet-rich fibrin application on implant stability. Study design: Five databases, namely, PubMed, Embase, Web of Science, Wiley, and China National Knowledge Infrastructure, were searched for reports published up to November 20, 2022. Randomized controlled trials (RCT), including parallel RCTs and split-mouth RCTs, with at least 10 patients/sites were considered for inclusion. Results: After screening based on the inclusion criteria, ten RCTs were included. Low heterogeneity was observed in study characteristics, outcome variables, and estimation scales (I2 = 27.2%, P = 0.19). The qualitative and meta-analysis results showed that PRF increased the effect of implant stabilizers after implant surgery. Conclusions: The results of the present systematic review and meta-analysis suggest that PRF can increase implant stability after implant surgery. PRF may also have a role in accelerating bone healing and tends to promote new bone formation at the implant site. |
| first_indexed | 2024-04-10T06:20:20Z |
| format | Article |
| id | doaj.art-2bf1cdc08fde438a87c24b9feaac8dc6 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-10T06:20:20Z |
| publishDate | 2023-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-2bf1cdc08fde438a87c24b9feaac8dc62023-03-02T05:00:26ZengElsevierHeliyon2405-84402023-02-0192e13196Clinical application of platelet-rich fibrin to enhance dental implant stability: A systematic review and meta-analysisShuai Guan0Tiepeng Xiao1Jiuping Bai2Chunliu Ning3Xingkui Zhang4Lei Yang5Xiangjun Li6Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Hebei Medical University and Hebei Key Laboratory of Stomatology, Shijiazhuang, 050017, PR ChinaThe Second Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050000, PR ChinaDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Hebei Medical University and Hebei Key Laboratory of Stomatology, Shijiazhuang, 050017, PR ChinaDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Hebei Medical University and Hebei Key Laboratory of Stomatology, Shijiazhuang, 050017, PR ChinaDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Hebei Medical University and Hebei Key Laboratory of Stomatology, Shijiazhuang, 050017, PR ChinaDepartment of Epidemiology and Statistics, School of Public Health, Hebei Key Laboratory of Environment and Human Health, Hebei Medical University, Shijiazhuang, 050017, PR ChinaDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Hebei Medical University and Hebei Key Laboratory of Stomatology, Shijiazhuang, 050017, PR China; Corresponding author.Objective: To investigate the effect of platelet-rich fibrin application on implant stability. Study design: Five databases, namely, PubMed, Embase, Web of Science, Wiley, and China National Knowledge Infrastructure, were searched for reports published up to November 20, 2022. Randomized controlled trials (RCT), including parallel RCTs and split-mouth RCTs, with at least 10 patients/sites were considered for inclusion. Results: After screening based on the inclusion criteria, ten RCTs were included. Low heterogeneity was observed in study characteristics, outcome variables, and estimation scales (I2 = 27.2%, P = 0.19). The qualitative and meta-analysis results showed that PRF increased the effect of implant stabilizers after implant surgery. Conclusions: The results of the present systematic review and meta-analysis suggest that PRF can increase implant stability after implant surgery. PRF may also have a role in accelerating bone healing and tends to promote new bone formation at the implant site.http://www.sciencedirect.com/science/article/pii/S2405844023004036Dental implantsPlatelet-rich fibrinImplant stabilityMeta-analysis |
| spellingShingle | Shuai Guan Tiepeng Xiao Jiuping Bai Chunliu Ning Xingkui Zhang Lei Yang Xiangjun Li Clinical application of platelet-rich fibrin to enhance dental implant stability: A systematic review and meta-analysis Heliyon Dental implants Platelet-rich fibrin Implant stability Meta-analysis |
| title | Clinical application of platelet-rich fibrin to enhance dental implant stability: A systematic review and meta-analysis |
| title_full | Clinical application of platelet-rich fibrin to enhance dental implant stability: A systematic review and meta-analysis |
| title_fullStr | Clinical application of platelet-rich fibrin to enhance dental implant stability: A systematic review and meta-analysis |
| title_full_unstemmed | Clinical application of platelet-rich fibrin to enhance dental implant stability: A systematic review and meta-analysis |
| title_short | Clinical application of platelet-rich fibrin to enhance dental implant stability: A systematic review and meta-analysis |
| title_sort | clinical application of platelet rich fibrin to enhance dental implant stability a systematic review and meta analysis |
| topic | Dental implants Platelet-rich fibrin Implant stability Meta-analysis |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023004036 |
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