The Impact of Excessive Fructose Intake on Adipose Tissue and the Development of Childhood Obesity
Worldwide, childhood obesity cases continue to rise, and its prevalence is known to increase the risk of non-communicable diseases typically found in adults, such as cardiovascular disease and type 2 diabetes mellitus. Thus, comprehending its multiple causes to build healthier approaches and revert...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/7/939 |
| _version_ | 1797212143005728768 |
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| author | Anna Karenina Azevedo-Martins Matheus Pedro Santos Julie Abayomi Natália Juliana Ramos Ferreira Fabiana S. Evangelista |
| author_facet | Anna Karenina Azevedo-Martins Matheus Pedro Santos Julie Abayomi Natália Juliana Ramos Ferreira Fabiana S. Evangelista |
| author_sort | Anna Karenina Azevedo-Martins |
| collection | DOAJ |
| description | Worldwide, childhood obesity cases continue to rise, and its prevalence is known to increase the risk of non-communicable diseases typically found in adults, such as cardiovascular disease and type 2 diabetes mellitus. Thus, comprehending its multiple causes to build healthier approaches and revert this scenario is urgent. Obesity development is strongly associated with high fructose intake since the excessive consumption of this highly lipogenic sugar leads to white fat accumulation and causes white adipose tissue (WAT) inflammation, oxidative stress, and dysregulated adipokine release. Unfortunately, the global consumption of fructose has increased dramatically in recent years, which is associated with the fact that fructose is not always evident to consumers, as it is commonly added as a sweetener in food and sugar-sweetened beverages (SSB). Therefore, here, we discuss the impact of excessive fructose intake on adipose tissue biology, its contribution to childhood obesity, and current strategies for reducing high fructose and/or free sugar intake. To achieve such reductions, we conclude that it is important that the population has access to reliable information about food ingredients via food labels. Consumers also need scientific education to understand potential health risks to themselves and their children. |
| first_indexed | 2024-04-24T10:37:41Z |
| format | Article |
| id | doaj.art-2bf2495a749f4a7581ab6430f57107c2 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-04-24T10:37:41Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-2bf2495a749f4a7581ab6430f57107c22024-04-12T13:24:10ZengMDPI AGNutrients2072-66432024-03-0116793910.3390/nu16070939The Impact of Excessive Fructose Intake on Adipose Tissue and the Development of Childhood ObesityAnna Karenina Azevedo-Martins0Matheus Pedro Santos1Julie Abayomi2Natália Juliana Ramos Ferreira3Fabiana S. Evangelista4Group of Study in Endocrinology and Metabolism, School of Arts, Sciences and Humanities, University of São Paulo, São Paulo 03828-000, BrazilGroup of Study in Endocrinology and Metabolism, School of Arts, Sciences and Humanities, University of São Paulo, São Paulo 03828-000, BrazilSchool of Medicine and Nutrition, Faculty of Health, Social Care and Medicine, Edge Hill University, Ormskirk L39 4QP, UKGroup of Study in Endocrinology and Metabolism, School of Arts, Sciences and Humanities, University of São Paulo, São Paulo 03828-000, BrazilGroup of Study in Endocrinology and Metabolism, School of Arts, Sciences and Humanities, University of São Paulo, São Paulo 03828-000, BrazilWorldwide, childhood obesity cases continue to rise, and its prevalence is known to increase the risk of non-communicable diseases typically found in adults, such as cardiovascular disease and type 2 diabetes mellitus. Thus, comprehending its multiple causes to build healthier approaches and revert this scenario is urgent. Obesity development is strongly associated with high fructose intake since the excessive consumption of this highly lipogenic sugar leads to white fat accumulation and causes white adipose tissue (WAT) inflammation, oxidative stress, and dysregulated adipokine release. Unfortunately, the global consumption of fructose has increased dramatically in recent years, which is associated with the fact that fructose is not always evident to consumers, as it is commonly added as a sweetener in food and sugar-sweetened beverages (SSB). Therefore, here, we discuss the impact of excessive fructose intake on adipose tissue biology, its contribution to childhood obesity, and current strategies for reducing high fructose and/or free sugar intake. To achieve such reductions, we conclude that it is important that the population has access to reliable information about food ingredients via food labels. Consumers also need scientific education to understand potential health risks to themselves and their children.https://www.mdpi.com/2072-6643/16/7/939fructosechildhood obesityadipose tissue |
| spellingShingle | Anna Karenina Azevedo-Martins Matheus Pedro Santos Julie Abayomi Natália Juliana Ramos Ferreira Fabiana S. Evangelista The Impact of Excessive Fructose Intake on Adipose Tissue and the Development of Childhood Obesity Nutrients fructose childhood obesity adipose tissue |
| title | The Impact of Excessive Fructose Intake on Adipose Tissue and the Development of Childhood Obesity |
| title_full | The Impact of Excessive Fructose Intake on Adipose Tissue and the Development of Childhood Obesity |
| title_fullStr | The Impact of Excessive Fructose Intake on Adipose Tissue and the Development of Childhood Obesity |
| title_full_unstemmed | The Impact of Excessive Fructose Intake on Adipose Tissue and the Development of Childhood Obesity |
| title_short | The Impact of Excessive Fructose Intake on Adipose Tissue and the Development of Childhood Obesity |
| title_sort | impact of excessive fructose intake on adipose tissue and the development of childhood obesity |
| topic | fructose childhood obesity adipose tissue |
| url | https://www.mdpi.com/2072-6643/16/7/939 |
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