SIRT1-mediated p53 deacetylation inhibits ferroptosis and alleviates heat stress-induced lung epithelial cells injury

SIRT1-mediated p53 deacetylation inhibits ferroptosis and alleviates heat stress-induced lung epithelial cells injury

Objective Acute lung injury (ALI) is a common complication of heat stroke (HS) and a direct cause of death. However, the mechanism underlying ALI following HS remains unclear.Method To investigate whether ferroptosis is involved in HS-ALI. We established a HS model of mice and mouse lung epithelial-...

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Bibliographic Details
Main Authors: Hui Chen, Xiaoping Lin, Xiaohong Yi, Xiaofeng Liu, Ranghui Yu, Wenhao Fan, Yaping Ling, Yanan Liu, Weidang Xie
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:International Journal of Hyperthermia
Subjects:
Heat stroke
acute lung injury
ferroptosis
SIRT1
p53
Online Access:https://www.tandfonline.com/doi/10.1080/02656736.2022.2094476

Internet

https://www.tandfonline.com/doi/10.1080/02656736.2022.2094476

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