In Vitro Differentiation of Preosteoblast-Like Cells, MC3T3-E1, to Adipocytes Is Enhanced by 1,25(OH)2 Vitamin D3

In Vitro Differentiation of Preosteoblast-Like Cells, MC3T3-E1, to Adipocytes Is Enhanced by 1,25(OH)2 Vitamin D3

Osteoblasts and adipocytes originate from common mesenchymal progenitor cells and are controlled by specific transcription factors. While 1,25-dihydroxyvitamin D3 (vitamin D) is known to be an important factor for osteoblast differentiation, there are conflicting reports regarding its effect on adip...

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Bibliographic Details
Main Authors: Elisha Pendleton, Nalini Chandar
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Endocrinology
Subjects:
vitamin D
osteoblasts
MC3T3
Rb1
adipogenic differentiation
transdifferentiation
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00128/full

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