The association of dietary resistance starch intake with all-cause and cause-specific mortality
BackgroundSeveral studies have estimated daily intake of resistant starch (RS), but no studies have investigated the relationship of RS intake with mortality.ObjectiveWe aimed to examine associations between RS intake and all-cause and cause-specific mortality.MethodsData from US National Health and...
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.1004667/full |
| _version_ | 1828276283364081664 |
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| author | Jiang Wan Xiaocong Li Ming Gu Qi Li Chuyun Wang Run Yuan Lin Li Xiang Li Shaodong Ye Jichun Chen |
| author_facet | Jiang Wan Xiaocong Li Ming Gu Qi Li Chuyun Wang Run Yuan Lin Li Xiang Li Shaodong Ye Jichun Chen |
| author_sort | Jiang Wan |
| collection | DOAJ |
| description | BackgroundSeveral studies have estimated daily intake of resistant starch (RS), but no studies have investigated the relationship of RS intake with mortality.ObjectiveWe aimed to examine associations between RS intake and all-cause and cause-specific mortality.MethodsData from US National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018 with 24-h dietary recall data was used in current study. The main exposure in this study was RS intake, and the main outcome was the mortality status of participants until December 31, 2019. The multivariable Cox proportional hazards regression models were developed to evaluate the hazard ratios (HRs) and 95% confidence interval (95% CI) of cardiovascular disease (CVD), cancer, and all-cause mortality associated with RS intake.ResultsA total of 42,586 US adults [mean (SD) age, 46.91 (16.88) years; 22,328 (52.43%) female] were included in the present analysis. During the 454,252 person-years of follow-up, 7,043 all-cause deaths occurred, including 1,809 deaths from CVD and 1,574 deaths from cancer. The multivariable-adjusted HRs for CVD, cancer, and all-cause mortality per quintile increase in RS intake were 1 (95%CI, 0.97–1.04), 0.96 (95%CI, 0.93–1), and 0.96 (95%CI, 0.95–0.98), respectively. The associations remained similar in the subgroup and sensitivity analyses.ConclusionHigher RS intake is significantly associated with lower cancer and all-cause mortality, but not significantly with CVD mortality. Future studies focusing on other populations with different food sources of RS and RS subtypes are needed to access the dose–response relationship and to improve global dietary recommendations. |
| first_indexed | 2024-04-13T06:55:51Z |
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| language | English |
| last_indexed | 2024-04-13T06:55:51Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-2bf87e6ea46048c3962c8b51f14b9a7e2022-12-22T02:57:15ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-12-01910.3389/fnut.2022.10046671004667The association of dietary resistance starch intake with all-cause and cause-specific mortalityJiang Wan0Xiaocong Li1Ming Gu2Qi Li3Chuyun Wang4Run Yuan5Lin Li6Xiang Li7Shaodong Ye8Jichun Chen9Department of Epidemiology, Key Laboratory of Cardiovascular Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaMedical Research and Biometrics Center, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Nutrition, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Nutrition, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Nutrition, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Nutrition, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Nutrition, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaBackgroundSeveral studies have estimated daily intake of resistant starch (RS), but no studies have investigated the relationship of RS intake with mortality.ObjectiveWe aimed to examine associations between RS intake and all-cause and cause-specific mortality.MethodsData from US National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018 with 24-h dietary recall data was used in current study. The main exposure in this study was RS intake, and the main outcome was the mortality status of participants until December 31, 2019. The multivariable Cox proportional hazards regression models were developed to evaluate the hazard ratios (HRs) and 95% confidence interval (95% CI) of cardiovascular disease (CVD), cancer, and all-cause mortality associated with RS intake.ResultsA total of 42,586 US adults [mean (SD) age, 46.91 (16.88) years; 22,328 (52.43%) female] were included in the present analysis. During the 454,252 person-years of follow-up, 7,043 all-cause deaths occurred, including 1,809 deaths from CVD and 1,574 deaths from cancer. The multivariable-adjusted HRs for CVD, cancer, and all-cause mortality per quintile increase in RS intake were 1 (95%CI, 0.97–1.04), 0.96 (95%CI, 0.93–1), and 0.96 (95%CI, 0.95–0.98), respectively. The associations remained similar in the subgroup and sensitivity analyses.ConclusionHigher RS intake is significantly associated with lower cancer and all-cause mortality, but not significantly with CVD mortality. Future studies focusing on other populations with different food sources of RS and RS subtypes are needed to access the dose–response relationship and to improve global dietary recommendations.https://www.frontiersin.org/articles/10.3389/fnut.2022.1004667/fulldietaryresistant starchmortalityCVDcardiovascular diseasecancer |
| spellingShingle | Jiang Wan Xiaocong Li Ming Gu Qi Li Chuyun Wang Run Yuan Lin Li Xiang Li Shaodong Ye Jichun Chen The association of dietary resistance starch intake with all-cause and cause-specific mortality Frontiers in Nutrition dietary resistant starch mortality CVD cardiovascular disease cancer |
| title | The association of dietary resistance starch intake with all-cause and cause-specific mortality |
| title_full | The association of dietary resistance starch intake with all-cause and cause-specific mortality |
| title_fullStr | The association of dietary resistance starch intake with all-cause and cause-specific mortality |
| title_full_unstemmed | The association of dietary resistance starch intake with all-cause and cause-specific mortality |
| title_short | The association of dietary resistance starch intake with all-cause and cause-specific mortality |
| title_sort | association of dietary resistance starch intake with all cause and cause specific mortality |
| topic | dietary resistant starch mortality CVD cardiovascular disease cancer |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.1004667/full |
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