Electrochemotherapy with Mitomycin C Potentiates Apoptosis Death by Inhibiting Autophagy in Squamous Carcinoma Cells

Electrochemotherapy with Mitomycin C Potentiates Apoptosis Death by Inhibiting Autophagy in Squamous Carcinoma Cells

We investigated the chemosensitizing effect of electroporation (EP), which, using electrical pulses, permeabilizes cancer cells to drugs. The study involved two human hypopharyngeal and tongue carcinoma cell lines. The surface and intracytoplasmic expression of P-gp were evaluated by flow cytometry,...

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Bibliographic Details
Main Authors: Maria Condello, Gloria D’Avack, Rosa Vona, Enrico Pierluigi Spugnini, Licia Scacco, Stefania Meschini
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
electrochemotherapy
mitomycin C
squamous carcinoma cell lines
drug resistance
apoptosis
autophagy
Online Access:https://www.mdpi.com/2072-6694/13/15/3867

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