A novel optical imaging probe for targeted visualization of NLRP3 inflammasomes in a mouse model of age-related macular degeneration

A novel optical imaging probe for targeted visualization of NLRP3 inflammasomes in a mouse model of age-related macular degeneration

PurposeWet form of age-related macular degeneration (wet AMD) is a progressive vascular disease that mainly affects older adults and causes severe and irreversible vision loss. A key complication of wet AMD is choroidal neovascularization (CNV), which may be driven in part by NLRP3 inflammasomes tha...

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Bibliographic Details
Main Authors:	Marcell E. Paguaga, John S. Penn, MD Imam Uddin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Medicine
Subjects:	age-related macular degeneration NLRP3 inflammasome macrophages optical imaging choroidal neovascularization CY-09
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2022.1047791/full

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