Prevention and management of chronic Hepatitis B
Chronic hepatitis B virus (HBV) infection affects an estimated 370 million people worldwide. HBV is endemic throughout the world, and insidiously causes liver damage over years and decades without any warning symptoms or signs. Up to 25-35% of infected individuals eventually die due to complications...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | International Journal of Preventive Medicine |
| Subjects: | |
| Online Access: | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2014;volume=5;issue=15;spage=200;epage=207;aulast=Bhat |
| _version_ | 1818112968823406592 |
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| author | Mamatha Bhat Peter Ghali Marc Deschenes Philip Wong |
| author_facet | Mamatha Bhat Peter Ghali Marc Deschenes Philip Wong |
| author_sort | Mamatha Bhat |
| collection | DOAJ |
| description | Chronic hepatitis B virus (HBV) infection affects an estimated 370 million people worldwide. HBV is endemic throughout the world, and insidiously causes liver damage over years and decades without any warning symptoms or signs. Up to 25-35% of infected individuals eventually die due to complications of liver cirrhosis and hepatocellular carcinoma (HCC) induced by HBV. Screening those individuals at risk of acquiring hepatitis B, and universal vaccination for prevention, would help in limiting the spread and public health repercussions of the virus. Although many new antiviral therapies have been developed for the management of hepatitis B, they still do not offer the possibility of cure. Most individuals who begin oral suppressive therapy will be indefinitely treated. Continuous suppression of HBV replication in individuals with advanced liver disease prolongs life, decreases the need for liver transplantation, and potentially reduces the risk for HCC. In this clinical review, we present a practical approach to prevention of HBV, its natural history and life cycle, as well as its management. |
| first_indexed | 2024-12-11T03:27:22Z |
| format | Article |
| id | doaj.art-2bfbcf14bdec433c83137b62bae4c2ea |
| institution | Directory Open Access Journal |
| issn | 2008-7802 2008-8213 |
| language | English |
| last_indexed | 2024-12-11T03:27:22Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Preventive Medicine |
| spelling | doaj.art-2bfbcf14bdec433c83137b62bae4c2ea2022-12-22T01:22:28ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132014-01-01515200207Prevention and management of chronic Hepatitis BMamatha BhatPeter GhaliMarc DeschenesPhilip WongChronic hepatitis B virus (HBV) infection affects an estimated 370 million people worldwide. HBV is endemic throughout the world, and insidiously causes liver damage over years and decades without any warning symptoms or signs. Up to 25-35% of infected individuals eventually die due to complications of liver cirrhosis and hepatocellular carcinoma (HCC) induced by HBV. Screening those individuals at risk of acquiring hepatitis B, and universal vaccination for prevention, would help in limiting the spread and public health repercussions of the virus. Although many new antiviral therapies have been developed for the management of hepatitis B, they still do not offer the possibility of cure. Most individuals who begin oral suppressive therapy will be indefinitely treated. Continuous suppression of HBV replication in individuals with advanced liver disease prolongs life, decreases the need for liver transplantation, and potentially reduces the risk for HCC. In this clinical review, we present a practical approach to prevention of HBV, its natural history and life cycle, as well as its management.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2014;volume=5;issue=15;spage=200;epage=207;aulast=BhatAntiviral treatmentdiagnosishepatitis Bprevention |
| spellingShingle | Mamatha Bhat Peter Ghali Marc Deschenes Philip Wong Prevention and management of chronic Hepatitis B International Journal of Preventive Medicine Antiviral treatment diagnosis hepatitis B prevention |
| title | Prevention and management of chronic Hepatitis B |
| title_full | Prevention and management of chronic Hepatitis B |
| title_fullStr | Prevention and management of chronic Hepatitis B |
| title_full_unstemmed | Prevention and management of chronic Hepatitis B |
| title_short | Prevention and management of chronic Hepatitis B |
| title_sort | prevention and management of chronic hepatitis b |
| topic | Antiviral treatment diagnosis hepatitis B prevention |
| url | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2014;volume=5;issue=15;spage=200;epage=207;aulast=Bhat |
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