A Larger Membrane Area Increases Cytokine Removal in Polymethyl Methacrylate Hemofilters

A Larger Membrane Area Increases Cytokine Removal in Polymethyl Methacrylate Hemofilters

Blood purification is performed to control cytokines in critically ill patients. The relationship between the clearance (CL) and the membrane area during adsorption is not clear. We hypothesized that the CL increases with the hydrophobic area when hydrophobic binding contributes to cytokine adsorpti...

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Bibliographic Details
Main Authors: Tomoyuki Nakamura, Kazuhiro Moriyama, Naohide Kuriyama, Yoshitaka Hara, Satoshi Komatsu, Takahiro Kawaji, Yu Kato, Takuma Ishihara, Ayumi Shintani, Osamu Nishida
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Membranes
Subjects:
adsorption
blood purification
clearance
hemofilters
HMGB-1
hydrophobic binding
Online Access:https://www.mdpi.com/2077-0375/12/8/811

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