The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age
An integrated analysis of GABA concentration, interhemispheric phase-based connectivity behavior and in healthy human participants revealed a task-specific association between GABA concentration and motor-cortical connectivity. These results shed light on how GABA is involved in neural oscillations...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-05-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03378-w |
| _version_ | 1811304789031518208 |
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| author | Kirstin-Friederike Heise Laura Rueda-Delgado Sima Chalavi Bradley R. King Thiago Santos Monteiro Richard A. E. Edden Dante Mantini Stephan P. Swinnen |
| author_facet | Kirstin-Friederike Heise Laura Rueda-Delgado Sima Chalavi Bradley R. King Thiago Santos Monteiro Richard A. E. Edden Dante Mantini Stephan P. Swinnen |
| author_sort | Kirstin-Friederike Heise |
| collection | DOAJ |
| description | An integrated analysis of GABA concentration, interhemispheric phase-based connectivity behavior and in healthy human participants revealed a task-specific association between GABA concentration and motor-cortical connectivity. These results shed light on how GABA is involved in neural oscillations and behavioral performance. |
| first_indexed | 2024-04-13T08:13:23Z |
| format | Article |
| id | doaj.art-2bff308e4e7d413ca1f2d8e14f9f5449 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-13T08:13:23Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-2bff308e4e7d413ca1f2d8e14f9f54492022-12-22T02:54:52ZengNature PortfolioCommunications Biology2399-36422022-05-015111710.1038/s42003-022-03378-wThe interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced ageKirstin-Friederike Heise0Laura Rueda-Delgado1Sima Chalavi2Bradley R. King3Thiago Santos Monteiro4Richard A. E. Edden5Dante Mantini6Stephan P. Swinnen7Department of Movement Sciences, Movement Control and Neuroplasticity Research Group, KU LeuvenDepartment of Movement Sciences, Movement Control and Neuroplasticity Research Group, KU LeuvenDepartment of Movement Sciences, Movement Control and Neuroplasticity Research Group, KU LeuvenDepartment of Movement Sciences, Movement Control and Neuroplasticity Research Group, KU LeuvenDepartment of Movement Sciences, Movement Control and Neuroplasticity Research Group, KU LeuvenThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of MedicineDepartment of Movement Sciences, Movement Control and Neuroplasticity Research Group, KU LeuvenDepartment of Movement Sciences, Movement Control and Neuroplasticity Research Group, KU LeuvenAn integrated analysis of GABA concentration, interhemispheric phase-based connectivity behavior and in healthy human participants revealed a task-specific association between GABA concentration and motor-cortical connectivity. These results shed light on how GABA is involved in neural oscillations and behavioral performance.https://doi.org/10.1038/s42003-022-03378-w |
| spellingShingle | Kirstin-Friederike Heise Laura Rueda-Delgado Sima Chalavi Bradley R. King Thiago Santos Monteiro Richard A. E. Edden Dante Mantini Stephan P. Swinnen The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age Communications Biology |
| title | The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age |
| title_full | The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age |
| title_fullStr | The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age |
| title_full_unstemmed | The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age |
| title_short | The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age |
| title_sort | interaction between endogenous gaba functional connectivity and behavioral flexibility is critically altered with advanced age |
| url | https://doi.org/10.1038/s42003-022-03378-w |
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